# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | A 485 | A-485 | Cell Proliferation EC50 | 0.4 | uM | ALA4886627 | uM | Homo sapiens | ||||
2. | ALA4550647 | 31 | IC50 | > | 10000 | nM | ALA4478293 | nM | Homo sapiens | |||
3. | Temozolomide | 1 | TGI | 0 | ALA4678446 | Active | Homo sapiens | |||||
4. | Pamiparib (BGB-290) | BDBM207624 | TGI | 0 | ALA4678445 | Not Active | Homo sapiens | |||||
5. | Pamiparib (BGB-290) | BDBM207624 | TGI | 0 | ALA4678444 | Active | Homo sapiens | |||||
6. | Pamiparib (BGB-290) | BDBM207624 | Activity | = | 50 | % | ALA4678443 | % | Homo sapiens | |||
7. | Temozolomide | 1 | Activity | = | 13 | % | ALA4678442 | % | Homo sapiens | |||
8. | Temozolomide | 1 | Activity | 0 | ALA4678441 | Not Active | Homo sapiens | |||||
9. | Pamiparib (BGB-290) | BDBM207624 | Activity | 0 | ALA4678440 | Active | Homo sapiens | |||||
10. | ALA4166144 | 19 | TGI | 0 | ALA4150449 | Dose-dependent effect | Homo sapiens | |||||
11. | ALA4166144 | 19 | TGI | = | 91.7 | % | ALA4150448 | % | Homo sapiens | |||
12. | ALA4166144 | 19 | TGI | = | 80.9 | % | ALA4150447 | % | Homo sapiens | |||
13. | ALA5078321 | 13 | IC50 | = | 20.7 | nM | ALA5034112 | 7.68 | nM | Homo sapiens | ||
14. | ALA1614701 | AZD-6244 | IC50 | = | 33.452 | uM | ALA2363504 | 4.48 | nM | Homo sapiens | ||
15. | SB590885 | 33, SB-590885 | IC50 | = | 35.476 | uM | ALA2363504 | 4.45 | nM | Homo sapiens | ||
16. | PD0325901 | 34, PD-0325901 | IC50 | = | 14.776 | uM | ALA2363504 | 4.83 | nM | Homo sapiens | ||
17. | AZD8055 | 10, AZD-8055 | IC50 | = | 0.055 | uM | ALA2363504 | 7.26 | nM | Homo sapiens | ||
18. | BEZ235 | SID124898663 | IC50 | = | 0.017 | uM | ALA2363504 | 7.76 | nM | Homo sapiens | ||
19. | Palbociclib | 43(table 3) | IC50 | = | 5.259 | uM | ALA2363504 | 5.28 | nM | Homo sapiens | ||
20. | MK-2206 | 17 | IC50 | = | 100.121 | uM | ALA2363504 | nM | Homo sapiens |