# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5288938 | PROTAC 1 | IC50 | = | 6.8 | nM | ALA5242504 | 8.17 | nM | Homo sapiens | ||
2. | GDC-0068 | 28, GDC-0068 | IC50 | = | 18 | nM | ALA5242504 | 7.75 | nM | Homo sapiens | ||
3. | GSK690693 | 3g, GSK-690693 | IC50 | = | 13 | nM | ALA5236804 | 7.89 | nM | Homo sapiens | ||
4. | MK-2206 | 17 | IC50 | = | 12 | nM | ALA5227204 | 7.92 | nM | Homo sapiens | ||
5. | Uprosertib | UPROSERTIB | IC50 | = | 1.4 | nM | ALA5225432 | 8.85 | nM | Homo sapiens | ||
6. | Afuresertib (GSK2110183) | AFURESERTIB | IC50 | = | 2 | nM | ALA5225432 | 8.70 | nM | Homo sapiens | ||
7. | BAY1125976 | BAY-1125976 | IC50 | = | 18 | nM | ALA5225412 | 7.75 | nM | Homo sapiens | ||
8. | MK-2206 2HCl | MK2206.2HCl | IC50 | = | 12 | nM | ALA5225409 | 7.92 | nM | Homo sapiens | ||
9. | Borussertib | EUB0000645a | IC50 | = | 56 | nM | ALA5225409 | 7.25 | nM | Homo sapiens | ||
10. | miransertib | MIRANSERTIB | IC50 | = | 4.5 | nM | ALA5225409 | 8.35 | nM | Homo sapiens | ||
11. | vevorisertib | VEVORISERTIB | IC50 | = | 0.81 | nM | ALA5225409 | 9.09 | nM | Homo sapiens | ||
12. | ALA5286570 | 56 | IC50 | = | 20 | nM | ALA5225381 | 7.70 | nM | Homo sapiens | ||
13. | MS15 | 62; MS15 | Activity | 0 | ALA5217270 | Active | Homo sapiens | |||||
14. | ALA5220918 | 64; MS15N2 | IC50 | = | 558 | nM | ALA5217245 | 6.25 | nM | Homo sapiens | ||
15. | ALA5220876 | 63; MS15N1 | IC50 | = | 86 | nM | ALA5217245 | 7.07 | nM | Homo sapiens | ||
16. | MS15 | 62; MS15 | IC50 | = | 90 | nM | ALA5217245 | 7.05 | nM | Homo sapiens | ||
17. | miransertib | MIRANSERTIB | IC50 | = | 1.4 | nM | ALA5217245 | 8.85 | nM | Homo sapiens | ||
18. | MS15 | 62; MS15 | Activity | 0 | ALA5217233 | Active | Homo sapiens | |||||
19. | BAY1125976 | BAY-1125976 | IC50 | = | 36 | nM | ALA5213034 | 7.44 | nM | Homo sapiens | ||
20. | MK-2206 2HCl | MK2206.2HCl | IC50 | = | 12 | nM | ALA5210378 | 7.92 | nM | Homo sapiens |