# | Name | Compound Key | Action Type | Relation | Activety Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3234454 | 21 | INH | 0 | ALA3242431 | Dose-dependent effect | % | Rattus norvegicus | ||||
2. | ALA3234453 | 19 | INH | 0 | ALA3242431 | Dose-dependent effect | % | Rattus norvegicus | ||||
3. | ALA3350781 | 27 | INH | 0 | ALA3242431 | Dose-dependent effect | % | Rattus norvegicus | ||||
4. | ALA3234446 | 2, K17F | INH | 0 | ALA3242431 | Dose-dependent effect | % | Rattus norvegicus | ||||
5. | ALA3234454 | 21 | Imax | = | 69 | % | ALA3242432 | % | Rattus norvegicus | |||
6. | ALA3234453 | 19 | Imax | = | 77 | % | ALA3242432 | % | Rattus norvegicus | |||
7. | ALA3350781 | 27 | Imax | = | 100 | % | ALA3242432 | % | Rattus norvegicus | |||
8. | ALA3234446 | 2, K17F | Imax | = | 85 | % | ALA3242432 | % | Rattus norvegicus | |||
9. | ALA3234454 | 21 | IC50 | = | 1.7 | uM | ALA3242431 | 5.77 | nM | Rattus norvegicus | ||
10. | ALA3234453 | 19 | IC50 | = | 3 | uM | ALA3242431 | 5.52 | nM | Rattus norvegicus | ||
11. | ALA3350781 | 27 | IC50 | = | 4.3 | uM | ALA3242431 | 5.37 | nM | Rattus norvegicus | ||
12. | ALA3234446 | 2, K17F | IC50 | = | 1.4 | 10'-3microM | ALA3242431 | 8.85 | nM | Rattus norvegicus | ||
13. | ALA3234454 | 21 | Activity | 0 | ALA3242428 | Not Active | Rattus norvegicus | |||||
14. | ALA3350781 | 27 | Activity | 0 | ALA3242427 | Active | Rattus norvegicus | |||||
15. | ALA3234464 | 40 | Activity | 0 | ALA3242423 | Not Active | Rattus norvegicus | |||||
16. | ALA3350785 | 39 | Activity | 0 | ALA3242423 | Active | Rattus norvegicus | |||||
17. | ALA3234462 | 20 | Activity | 0 | ALA3242423 | Active | Rattus norvegicus | |||||
18. | ALA3234461 | 38 | Activity | 0 | ALA3242423 | Active | Rattus norvegicus | |||||
19. | ALA3234460 | 37 | Activity | 0 | ALA3242423 | Not Active | Rattus norvegicus | |||||
20. | ALA3234454 | 21 | Activity | 0 | ALA3242423 | Not Active | Rattus norvegicus |