# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Pemetrexed | 2 (LY-231514) | FC | = | 10 | ALA3412863 | Homo sapiens | |||||
2. | ALA3409335 | 9 | FC | = | 3 | ALA3412863 | Homo sapiens | |||||
3. | ALA3409336 | 10 | INH | 0 | ALA3412861 | Not Active | % | Homo sapiens | ||||
4. | ALA3409335 | 9 | INH | 0 | ALA3412861 | Active | % | Homo sapiens | ||||
5. | ALA3409334 | 8 | INH | 0 | ALA3412861 | Active | % | Homo sapiens | ||||
6. | ALA590740 | 1 | INH | 0 | ALA3412861 | Not Active | % | Homo sapiens | ||||
7. | ALA4437824 | 4 | INH | 0 | ALA4432150 | Active | % | Homo sapiens | ||||
8. | ALA4467936 | 9 | INH | 0 | ALA4432150 | Active | % | Homo sapiens | ||||
9. | ALA4447805 | 8 | INH | 0 | ALA4432150 | Active | % | Homo sapiens | ||||
10. | ALA4553188 | 7 | INH | 0 | ALA4432150 | Active | % | Homo sapiens | ||||
11. | ALA4444011 | 6 | INH | 0 | ALA4432150 | Active | % | Homo sapiens | ||||
12. | ALA4471269 | 5 | INH | 0 | ALA4432150 | Active | % | Homo sapiens | ||||
13. | ALA1834488 | 3 | INH | = | 50 | % | ALA4714613 | % | Homo sapiens | |||
14. | ALA4790375 | 5 | INH | 0 | ALA4714613 | Active | % | Homo sapiens | ||||
15. | ALA4741259 | 3 | INH | 0 | ALA4714613 | Active | % | Homo sapiens | ||||
16. | [³H]methotrexate | 138 | Ki | = | 0.88 | uM | ALA4714608 | 6.06 | nM | Homo sapiens | ||
17. | Pemetrexed | 2 (LY-231514) | Ki | > | 200 | uM | ALA4714608 | nM | Homo sapiens | |||
18. | ALA4755197 | 9 | Ki | = | 8.03 | uM | ALA4714608 | 5.09 | nM | Homo sapiens | ||
19. | ALA4783397 | 8 | Ki | = | 1.07 | uM | ALA4714608 | 5.97 | nM | Homo sapiens | ||
20. | ALA4761741 | 7 | Ki | = | 8.37 | uM | ALA4714608 | 5.08 | nM | Homo sapiens |