# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3793226 | 1; GSK945237 | CLH | < | 0.6 | ml/min | ALA3795001 | ml/min | Canis lupus familiaris | |||
2. | ALA3774827 | 29 | Stability | 0 | ALA3777092 | Not Determined | % | Canis lupus familiaris | ||||
3. | ALA3775875 | 28 | Stability | 0 | ALA3777092 | Not Determined | % | Canis lupus familiaris | ||||
4. | ALA3775504 | 26 | Stability | = | 83.8 | % | ALA3777092 | % | Canis lupus familiaris | |||
5. | ALA3627897 | 12 | Drug metabolism | 0 | ALA3778029 | metabolite_detected | Canis lupus familiaris | |||||
6. | ALA3775352 | M538d | Drug metabolism | 0 | ALA3778028 | metabolite_detected | Canis lupus familiaris | |||||
7. | ALA3775906 | M538c | Drug metabolism | 0 | ALA3778028 | metabolite_detected | Canis lupus familiaris | |||||
8. | ALA3774998 | M538b | Drug metabolism | 0 | ALA3778028 | metabolite_detected | Canis lupus familiaris | |||||
9. | ALA3774670 | M538a | Drug metabolism | = | 0.14 | % | ALA3778028 | % | Canis lupus familiaris | |||
10. | ALA3627897 | 12 | Drug metabolism | 0 | ALA3778027 | metabolite_detected | Canis lupus familiaris | |||||
11. | CP-466722 | SID137275943 | t1/2 | = | 0.6 | hr | ALA3768366 | hr | Canis lupus familiaris | |||
12. | ALA3764300 | 20 | t1/2 | > | 4 | hr | ALA3768366 | hr | Canis lupus familiaris | |||
13. | ALA3763358 | 27g | t1/2 | > | 4 | hr | ALA3768366 | hr | Canis lupus familiaris | |||
14. | ALA3764768 | 27n | t1/2 | > | 4 | hr | ALA3768366 | hr | Canis lupus familiaris | |||
15. | CP-466722 | SID137275943 | CLH | = | 52.5 | ml/min.kg | ALA3768370 | mL.min-1.kg-1 | Canis lupus familiaris | |||
16. | ALA3764300 | 20 | CLH | < | 8.3 | ml/min.kg | ALA3768370 | mL.min-1.kg-1 | Canis lupus familiaris | |||
17. | ALA3763358 | 27g | CLH | < | 8.3 | ml/min.kg | ALA3768370 | mL.min-1.kg-1 | Canis lupus familiaris | |||
18. | ALA3764768 | 27n | CLH | < | 7.9 | ml/min.kg | ALA3768370 | mL.min-1.kg-1 | Canis lupus familiaris | |||
19. | vibegron | VIBEGRON | CLH | = | 13 | ml/min.kg | ALA3768502 | mL.min-1.kg-1 | Canis lupus familiaris | |||
20. | ALA3763934 | 24 | CLH | = | 13 | ml/min.kg | ALA3768502 | mL.min-1.kg-1 | Canis lupus familiaris |