# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3787059 | 3 | Tmax | = | 0.5 | hr | ALA3790353 | hr | Rattus norvegicus | |||
2. | ALA3787059 | 3 | Cmax | = | 8.91 | ng/g | ALA3790354 | ng/g | Rattus norvegicus | |||
3. | ALA3787059 | 3 | Kel | = | 0.05 | /hr | ALA3790355 | /hr | Rattus norvegicus | |||
4. | ALA3787059 | 3 | beta t1/2 | = | 15.06 | hr | ALA3790356 | hr | Rattus norvegicus | |||
5. | ALA3787059 | 3 | AUC | = | 221.03 | ng/g.hr | ALA3790357 | ng/g.hr | Rattus norvegicus | |||
6. | 4-Aminosalicylic acid | 3 | Drug metabolism | 0 | ALA3756660 | metabolite_detected | Rattus norvegicus | |||||
7. | ALA3754178 | 6; 4-ASA-Glu | Drug metabolism | = | 7.9 | % | ALA3756659 | % | Rattus norvegicus | |||
8. | 4-Aminosalicylic acid | 3 | Drug metabolism | 0 | ALA3756652 | metabolite_detected | Rattus norvegicus | |||||
9. | ALA3754178 | 6; 4-ASA-Glu | Drug metabolism | = | 8.2 | % | ALA3756651 | % | Rattus norvegicus | |||
10. | ALA3542310 | [14C]Sunitinib, [14C]Sunitinib L-malate | Radiolabel recovery | = | 0.64 | ugequiv | ALA3541493 | ugequiv | Rattus norvegicus | |||
11. | ALA3542310 | [14C]Sunitinib, [14C]Sunitinib L-malate | Radiolabel recovery | = | 8.54 | ugequiv | ALA3533999 | ugequiv | Rattus norvegicus | |||
12. | ALA3542310 | [14C]Sunitinib, [14C]Sunitinib L-malate | Radiolabel recovery | = | 15.45 | ugequiv | ALA3534444 | ugequiv | Rattus norvegicus | |||
13. | ALA3542310 | [14C]Sunitinib, [14C]Sunitinib L-malate | Radiolabel recovery | = | 0.06 | ugequiv | ALA3534198 | ugequiv | Rattus norvegicus | |||
14. | ALA3526603 | M2 | Drug metabolism | 0 | ALA3532870 | metabolite_not_detected | Rattus norvegicus | |||||
15. | ALA80254 | 10 | Drug uptake | < | 1 | % | ALA3532870 | % | Rattus norvegicus | |||
16. | ALA3527012 | [14C]CS-1036 | Radiolabel recovery | = | 11.9 | ngequiv/g | ALA3530749 | ngequiv/g | Rattus norvegicus | |||
17. | ALA3527012 | [14C]CS-1036 | Radiolabel recovery | = | 41 | ngequiv/g | ALA3529673 | ngequiv/g | Rattus norvegicus | |||
18. | ALA3527012 | [14C]CS-1036 | Radiolabel recovery | = | 129 | ngequiv/g | ALA3527873 | ngequiv/g | Rattus norvegicus | |||
19. | ALA3527012 | [14C]CS-1036 | Radiolabel recovery | = | 23.9 | ngequiv/g | ALA3530721 | ngequiv/g | Rattus norvegicus | |||
20. | ALA3527012 | [14C]CS-1036 | Radiolabel recovery | = | 135 | ngequiv/g | ALA3528064 | ngequiv/g | Rattus norvegicus |