Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	4-[6-[4-(4-methylpiperazin-1-yl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline	13r	IC50	=	25.2	nM	ALA2390527	7.60		nM	Mus musculus
2.	ALA2385600	7d	IC50	=	94.1	nM	ALA2390527	7.03		nM	Mus musculus
3.	LDN 212854	13m	IC50	=	117	nM	ALA2390527	6.93		nM	Mus musculus
4.	4-[4-[3-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-6-yl]phenyl]morpholine	13a	IC50	=	141	nM	ALA2390527	6.85		nM	Mus musculus
5.	ML 347	50	IC50	=	152	nM	ALA2390527	6.82		nM	Mus musculus
6.	ALA2385588	13j	IC50	=	246	nM	ALA2390527	6.61		nM	Mus musculus
7.	ALA2385585	13g	IC50	=	418	nM	ALA2390527	6.38		nM	Mus musculus
8.	ALA2385595	13q	IC50	=	523	nM	ALA2390527	6.28		nM	Mus musculus
9.	ALA2385581	13c	IC50	=	529	nM	ALA2390527	6.28		nM	Mus musculus
10.	ALA2385592	13n	IC50	=	2636	nM	ALA2390527	5.58		nM	Mus musculus
11.	ALA2385578	7n	IC50	=	4571	nM	ALA2390527	5.34		nM	Mus musculus
12.	ALA2385403	7h	IC50	=	6732	nM	ALA2390527	5.17		nM	Mus musculus
13.	ALA511563	52	IC50	<	1	nM	ALA2390527			nM	Mus musculus
14.	4-[4-(3-quinolin-4-ylpyrazolo[1,5-a]pyrimidin-6-yl)phenyl]morpholine	13d	IC50	<	1	nM	ALA2390527			nM	Mus musculus
15.	ALA2385586	13h	IC50	<	1	nM	ALA2390527			nM	Mus musculus
16.	ALA2385598	7a	IC50		0		ALA2390527		Not Active		Mus musculus
17.	ALA467142	49	IC50		0		ALA2390527		Not Active		Mus musculus
18.	ALA2385599	7c	IC50		0		ALA2390527		Not Active		Mus musculus
19.	ALA2385601	7e	IC50		0		ALA2390527		Not Active		Mus musculus
20.	ALA454786	51	IC50		0		ALA2390527		Not Active		Mus musculus