# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2402081 | 37 | INH | = | 7 | % | ALA2405929 | % | Homo sapiens | |||
2. | ALA5169393 | 11 | INH | = | 83 | % | ALA5157124 | % | Homo sapiens | |||
3. | BI 605906 | BI605906 | % Ctrl | 82 | % | ALA4887379 | Not Active | % | Homo sapiens | |||
4. | ALA4475494 | 19 | % Inhibition | 13.5 | % | ALA4885928 | Not Active | % | Homo sapiens | |||
5. | Skepinone-L | 2, Skepinone-L | % Residual activity with Skepinone-L | 105 | % | ALA4883860 | Not Active | % | Homo sapiens | |||
6. | MLI-2 | 1; MLi-2 | % Inhibition | 8.751 | % | ALA4882684 | Not Active | % | Homo sapiens | |||
7. | ALA3417525 | 69, BI665915 | % Ctrl | 94 | % | ALA4881913 | Not Active | % | Homo sapiens | |||
8. | ALA3401550 | 7 | Time | < | 1.4 | min | ALA3404923 | hr | Homo sapiens | |||
9. | ALA3401551 | 8 | Time | = | 1626 | min | ALA3404923 | hr | Homo sapiens | |||
10. | ALA4461493 | 2 | INH | > | 50 | % | ALA4426350 | % | Homo sapiens | |||
11. | Sorafenib | 5 | INH | > | 50 | % | ALA4426350 | % | Homo sapiens | |||
12. | ALA4530828 | 12 | INH | > | 30 | % | ALA4426336 | % | Homo sapiens | |||
13. | ALA4450385 | 24 | IC50 | = | 99.9 | nM | ALA4426335 | 7.00 | nM | Homo sapiens | ||
14. | ALA4451530 | 23 | IC50 | = | 157 | nM | ALA4426335 | 6.80 | nM | Homo sapiens | ||
15. | ALA4472665 | 22 | IC50 | = | 40.1 | nM | ALA4426335 | 7.40 | nM | Homo sapiens | ||
16. | ALA4568245 | 21 | IC50 | = | 14.7 | nM | ALA4426335 | 7.83 | nM | Homo sapiens | ||
17. | 1-[(3S)-1-[2-(methylamino)pyrimidin-4-yl]pyrrolidin-3-yl]-3-[4-(morpholin-4-ylmethyl)-3-(trifluoromethyl)phenyl]urea | 20 | IC50 | = | 17.4 | nM | ALA4426335 | 7.76 | nM | Homo sapiens | ||
18. | ALA4514427 | 19 | IC50 | = | 20.5 | nM | ALA4426335 | 7.69 | nM | Homo sapiens | ||
19. | ALA4586753 | 18 | IC50 | = | 44.1 | nM | ALA4426335 | 7.36 | nM | Homo sapiens | ||
20. | ALA4553528 | 17 | IC50 | = | 5012 | nM | ALA4426335 | 5.30 | nM | Homo sapiens |