# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | OF-1 | 8 | dTm | = | 3.3 | K | ALA5214240 | K | Homo sapiens | |||
2. | NI-57 | 76; NI-57 | Kd | = | 410 | nM | ALA5214161 | 6.39 | nM | Homo sapiens | ||
3. | NI-57 | 76; NI-57 | IC50 | = | 140 | nM | ALA5214160 | 6.85 | nM | Homo sapiens | ||
4. | GSK 4027 | (R,R)-32; GSK4027 | Ki | = | 100 | nM | ALA5214225 | 7.00 | nM | Homo sapiens | ||
5. | BAY-299 | 5b; atropisomer 2 | IC50 | = | 5.55 | uM | ALA5214118 | 5.26 | nM | Homo sapiens | ||
6. | PFI 4 | 11 | Kd | = | 1000 | nM | ALA5214181 | 6.00 | nM | Homo sapiens | ||
7. | OF-1 | 8 | Kd | = | 2406 | nM | ALA5210551 | 5.62 | nM | Homo sapiens | ||
8. | NI-57 | 76; NI-57 | IC50 | = | 1010 | nM | ALA5210537 | 6.00 | nM | Homo sapiens | ||
9. | OF-1 | 8 | EC50 | > | 500 | nM | ALA5210072 | nM | Homo sapiens | |||
10. | ALA5205457 | 3r; ZLD2218 | IC50 | > | 1 | uM | ALA5158667 | nM | Homo sapiens | |||
11. | ALA4451357 | 19 | Activity | = | 70 | % | ALA4415516 | % | Homo sapiens | |||
12. | MS31 | 3; MS31 | Activity | 0 | ALA4377341 | Not Active | Homo sapiens | |||||
13. | ALA4780530 | 3 | IC50 | > | 15 | uM | ALA4717003 | nM | Homo sapiens | |||
14. | ALA4449894 | (S,S)-32 | pKd | = | 6.9 | ALA4359601 | 6.90 | nM | Homo sapiens | |||
15. | ALA4574669 | (R,R)-36n | deltaTm | = | 1.7 | degrees C | ALA4351630 | degrees C | Homo sapiens | |||
16. | ALA4574669 | (R,R)-36n | Activity | 0 | ALA4351650 | Active | Homo sapiens | |||||
17. | ALA3926851 | BDBM249277 | Kd | > | 10000 | nM | ALA4332535 | nM | Homo sapiens | |||
18. | N-(4-Bromo-3-(piperidin-1-ylsulfonyl)phenyl)-2-(4-cyclopropyl-4-methyl-2,5-dioxoimidazolidin-1-yl)acetamide | 23 | pIC50 | = | 5 | ALA4313229 | 5.00 | nM | Homo sapiens | |||
19. | ALA1360726 | SID24404909 | INH | 0 | ALA4272102 | Not Active | % | Homo sapiens | ||||
20. | ALA4204052 | 9 | Activity | = | 100 | % | ALA4198520 | % | Homo sapiens |