Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5277519	137; BI-9321	IC50	=	203	nM	ALA5232465	6.69		nM	Homo sapiens
2.	ALA5265919	136	Kd	=	160	uM	ALA5232464	3.80		nM	Homo sapiens
3.	ALA5270364	135	Kd	=	731	uM	ALA5232464	3.14		nM	Homo sapiens
4.	ALA5277519	137; BI-9321	Kd	=	166	uM	ALA5232464			nM	Homo sapiens
5.	ALA4749457	Table 1, R9C5	Kd	=	300	uM	ALA5232464	3.52		nM	Homo sapiens
6.	A 366	12, A-366	EC50	>	50	uM	ALA5214734			nM	Homo sapiens
7.	OICR-9429	16d; OICR-9429	% activity remaining	>	90	%	ALA5213724			%	Homo sapiens
8.	GSK591	GSK591	% of inhibition	=	75	%	ALA5214626			%	Homo sapiens
9.	ALA5195436	9; MS159	INH		0		ALA5141706		NA	%	Homo sapiens
10.	ALA5170450	8; MS8511	INH	>	50	%	ALA5129696			%	Homo sapiens
11.	ALA4778517	Table 1, R9C6	IC50	=	0.2	uM	ALA5124716	6.70		nM	Homo sapiens
12.	MR837	3f	Kd	=	91	nM	ALA5124715	7.04		nM	Homo sapiens
13.	Ibiglustat	VENGLUSTAT	INH	=	50	%	ALA5119879			%	Homo sapiens
14.	Ibiglustat	VENGLUSTAT	INH		0		ALA5119842		NA	%	Homo sapiens
15.	Dot1L-IN-4	10	INH		0		ALA4411216		Not Active	%	Homo sapiens
16.	MS31	3; MS31	INH		0		ALA4377329		Not Active	%	Homo sapiens
17.	MR837	3f	Activity		0		ALA4736945		Not Active		Homo sapiens
18.	ALA4797205	1	Activity		0		ALA4736940		Not Active		Homo sapiens
19.	ALA4778517	Table 1, R9C6	Kd	=	0.17	uM	ALA4705999	6.77		nM	Homo sapiens
20.	ALA4749457	Table 1, R9C5	Kd	=	300	uM	ALA4705999	3.52		nM	Homo sapiens