# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | vibegron | VIBEGRON | max activation | = | 103 | % | ALA3767597 | % | Macaca mulatta | |||
2. | ALA3765335 | 22 | max activation | = | 91 | % | ALA3767597 | % | Macaca mulatta | |||
3. | ALA3764088 | 18 | max activation | 0 | ALA3767597 | Not Determined | Macaca mulatta | |||||
4. | L-796568 free base | 2 | max activation | = | 17 | % | ALA3767597 | % | Macaca mulatta | |||
5. | vibegron | VIBEGRON | EC50 | = | 7.1 | nM | ALA3768725 | 8.15 | nM | Macaca mulatta | ||
6. | ALA3765335 | 22 | EC50 | = | 12 | nM | ALA3768725 | 7.92 | nM | Macaca mulatta | ||
7. | ALA3764088 | 18 | EC50 | 0 | ALA3768725 | Not Determined | Macaca mulatta | |||||
8. | L-796568 free base | 2 | EC50 | = | 17 | nM | ALA3768725 | 7.77 | nM | Macaca mulatta | ||
9. | vibegron | VIBEGRON | max activation | = | 87 | % | ALA3768723 | % | Macaca mulatta | |||
10. | ALA3765335 | 22 | max activation | = | 91 | % | ALA3768723 | % | Macaca mulatta | |||
11. | ALA3764088 | 18 | max activation | = | 91 | % | ALA3768723 | % | Macaca mulatta | |||
12. | L-796568 free base | 2 | max activation | = | 81 | % | ALA3768723 | % | Macaca mulatta | |||
13. | vibegron | VIBEGRON | EC50 | = | 0.57 | nM | ALA3768722 | 9.24 | nM | Macaca mulatta | ||
14. | ALA3765335 | 22 | EC50 | = | 2.5 | nM | ALA3768722 | 8.60 | nM | Macaca mulatta | ||
15. | ALA3764088 | 18 | EC50 | = | 3.5 | nM | ALA3768722 | 8.46 | nM | Macaca mulatta | ||
16. | L-796568 free base | 2 | EC50 | = | 0.43 | nM | ALA3768722 | 9.37 | nM | Macaca mulatta | ||
17. | ALA3128194 | 11a | EC50 | = | 0.06 | nM | ALA3128810 | 10.22 | nM | Macaca mulatta | ||
18. | ALA3128178 | 19 | EC50 | = | 2 | nM | ALA3128810 | 8.70 | nM | Macaca mulatta | ||
19. | ALA3128188 | 29 | EC50 | = | 4.7 | nM | ALA3128810 | 8.33 | nM | Macaca mulatta | ||
20. | ALA3128194 | 11a | Activity | = | 78 | % | ALA3128809 | % | Macaca mulatta |