# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3799831 | 16 | CLH | = | 21 | ml/min | ALA3802912 | ml/min | Mus musculus | |||
2. | ALA3775940 | 36 | CLH | = | 38.1 | uL/min | ALA3776070 | uL/min | Mus musculus | |||
3. | 3-[2-[5-(3-chloro-4-propan-2-yloxyphenyl)-1,3,4-thiadiazol-2-yl]-3-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]propanoic acid | 43 | CLH | < | 0.85 | mg/min/g | ALA3772387 | mg/min/g | Mus musculus | |||
4. | ALA3771118 | 4a; PF-06761281 | CLH | < | 6 | uL/min | ALA3773099 | uL/min | Mus musculus | |||
5. | ALA3758840 | 25 | Stability | = | 37 | % | ALA3762192 | % | Mus musculus | |||
6. | ALA3758840 | 25 | Drug metabolism | 0 | ALA3761657 | metabolite_detected | Mus musculus | |||||
7. | ALA3758840 | 25 | Drug metabolism | 0 | ALA3761655 | metabolite_detected | Mus musculus | |||||
8. | ALA3758840 | 25 | t1/2 | = | 79 | min | ALA3761653 | hr | Mus musculus | |||
9. | ALA3758840 | 25 | CLH | = | 8.7 | uL/min | ALA3761651 | uL/min | Mus musculus | |||
10. | CB-5083 | 71 | t1/2 | = | 172 | min | ALA3749476 | hr | Mus musculus | |||
11. | ALA3740897 | 14f; AZ0108 | CLH | = | 9 | uL/min | ALA3743835 | uL/min | Mus musculus | |||
12. | AZ9482 | 1; AZ9482 | CLH | = | 198 | uL/min | ALA3743835 | uL/min | Mus musculus | |||
13. | ALA3734797 | 16 | EC50 | = | 55 | nM | ALA3737423 | 7.26 | nM | Mus musculus | ||
14. | ALA3634394 | 8; IDX320 | CC50 | > | 10 | uM | ALA3637612 | nM | Mus musculus | |||
15. | ALA3623127 | 23, BMS-641988 | Drug metabolism | = | 0 | pmol/min | ALA3624805 | pmol/min | Mus musculus | |||
16. | ALA5179082 | 26 | Activity | = | 9.2 | % | ALA5158913 | % | Mus musculus | |||
17. | ALA5195557 | 25 | Activity | = | 7.9 | % | ALA5158913 | % | Mus musculus | |||
18. | ALA5172775 | 24 | Activity | = | 8.1 | % | ALA5158913 | % | Mus musculus | |||
19. | ALA5203031 | 23 | Activity | = | 7.9 | % | ALA5158913 | % | Mus musculus | |||
20. | ALA5176987 | 22 | Activity | = | 11.4 | % | ALA5158913 | % | Mus musculus |