# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Lithocholic acid | LCA | Activity | 0 | ALA3294717 | Active | Danio rerio | |||||
2. | ALA3220718 | Gemini-0097 | Kd | = | 1.8 | uM | ALA3222534 | 5.75 | nM | Danio rerio | ||
3. | ALA3220717 | Gemini-0072 | Kd | = | 1.8 | uM | ALA3222534 | 5.75 | nM | Danio rerio | ||
4. | ALA3220716 | Gemini | Kd | = | 3.3 | uM | ALA3222534 | 5.48 | nM | Danio rerio | ||
5. | ALA3220718 | Gemini-0097 | FC | = | 5 | ALA3222527 | Danio rerio | |||||
6. | ALA3220717 | Gemini-0072 | FC | = | 8 | ALA3222527 | Danio rerio | |||||
7. | ALA3220718 | Gemini-0097 | EC50 | = | 0.25 | nM | ALA3222526 | 9.60 | nM | Danio rerio | ||
8. | ALA3220717 | Gemini-0072 | EC50 | = | 0.15 | nM | ALA3222526 | 9.82 | nM | Danio rerio | ||
9. | ALA846 | 1 | EC50 | = | 5.5 | nM | ALA3222526 | 8.26 | nM | Danio rerio | ||
10. | ALA3220716 | Gemini | EC50 | = | 1.2 | nM | ALA3222526 | 8.92 | nM | Danio rerio | ||
11. | ALA3220718 | Gemini-0097 | FC | = | 22 | ALA3222525 | Danio rerio | |||||
12. | ALA3220717 | Gemini-0072 | FC | = | 36 | ALA3222525 | Danio rerio | |||||
13. | ALA4066758 | 1 | EC50 | > | 0.1 | uM | ALA4021081 | nM | Danio rerio | |||
14. | ALA4088053 | 2 | EC50 | > | 0.1 | uM | ALA4021081 | nM | Danio rerio | |||
15. | ALA4060864 | 3 | EC50 | > | 0.1 | uM | ALA4021081 | nM | Danio rerio | |||
16. | Impurity B of Calcitriol | 1,25(OH)2D3 | EC50 | = | 1.4 | 10'-10M | ALA4021081 | 9.85 | nM | Danio rerio | ||
17. | ALA4060864 | 3 | Activity | 0 | ALA4021079 | Active | Danio rerio | |||||
18. | ALA4066758 | 1 | Efficacy | = | 100 | % | ALA4021082 | % | Danio rerio | |||
19. | ALA4088053 | 2 | Efficacy | = | 47 | % | ALA4021082 | % | Danio rerio | |||
20. | ALA4060864 | 3 | Efficacy | = | 90 | % | ALA4021082 | % | Danio rerio |