Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ML417	20; ML417	INH	=	88	%	ALA4406553			%	Homo sapiens
2.	7β, 25-dihydroxycholesterol	17	EC50	=	2.1	nM	ALA4718952	8.68		nM	Homo sapiens
3.	7α,27-dihydroxycholesterol	8	EC50	=	1.3	nM	ALA4718952	8.89		nM	Homo sapiens
4.	ALA4776911	9	EC50	=	51	nM	ALA4718952	7.29		nM	Homo sapiens
5.	7α,25-dihydroxycholesterol	5; 7alpha,25-OHC	EC50	=	140	pM	ALA4718952	9.85		nM	Homo sapiens
6.	ALA4779254	12	Emax	=	122	%	ALA4718939			%	Homo sapiens
7.	ALA4757291	13	Emax	=	100	%	ALA4718939			%	Homo sapiens
8.	7α,25-dihydroxycholesterol	5; 7alpha,25-OHC	Emax	=	100	%	ALA4718939			%	Homo sapiens
9.	ALA4779254	12	EC50	=	0.102	nM	ALA4718936	9.99		nM	Homo sapiens
10.	ALA4757291	13	EC50	=	4.1	nM	ALA4718936	8.39		nM	Homo sapiens
11.	7α,25-dihydroxycholesterol	5; 7alpha,25-OHC	EC50	=	0.032	nM	ALA4718936	10.49		nM	Homo sapiens
12.	ALA3480577	DDD01251909	Mean fold stimulation		0.475		ALA4883436				Homo sapiens
13.	ALA3561875	SID174315876	IC50	=	0.478	uM	ALA3561999	6.32	active	nM	Homo sapiens
14.	ALA3561867	SID174315862	IC50	=	0.31	uM	ALA3561999	6.51	active	nM	Homo sapiens
15.	ALA3561862	SID174315878	IC50	>	1	uM	ALA3561999		inactive	nM	Homo sapiens
16.	ALA3561859	SID162009964	IC50	=	0.003	uM	ALA3561999	8.46	active	nM	Homo sapiens
17.	ALA3561833	SID162009886	IC50	=	0.024	uM	ALA3561999	7.62	active	nM	Homo sapiens
18.	ALA3561800	SID162009941	IC50	=	0.098	uM	ALA3561999	7.01	active	nM	Homo sapiens
19.	ALA3561798	SID174315884	IC50	=	0.002	uM	ALA3561999	8.65	active	nM	Homo sapiens
20.	ALA3561756	SID174315886	IC50	=	0.002	uM	ALA3561999	8.82	active	nM	Homo sapiens