# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Decernotinib (VX-509) | DECERNOTINIB | IC50 | = | 16400 | nM | ALA3299206 | 4.79 | nM | Homo sapiens | ||
2. | GLPG0634 analogue | SID174006711 | IC50 | = | 13362 | nM | ALA3299206 | 4.87 | nM | Homo sapiens | ||
3. | Decernotinib (VX-509) | DECERNOTINIB | IC50 | = | 11200 | nM | ALA3299208 | 4.95 | nM | Homo sapiens | ||
4. | GLPG0634 analogue | SID174006711 | IC50 | = | 10123 | nM | ALA3299208 | 5.00 | nM | Homo sapiens | ||
5. | Ruxolitinib (INCB018424) | 3, INCB-018424 | IC50 | = | 1090 | nM | ALA3299206 | 5.96 | nM | Homo sapiens | ||
6. | Ruxolitinib (INCB018424) | 3, INCB-018424 | IC50 | = | 818 | nM | ALA3299208 | 6.09 | nM | Homo sapiens | ||
7. | racemic-tofacitinib | CP-690550 | IC50 | = | 409 | nM | ALA3299206 | 6.39 | nM | Homo sapiens | ||
8. | racemic-tofacitinib | CP-690550 | IC50 | = | 229 | nM | ALA3299208 | 6.64 | nM | Homo sapiens | ||
9. | Baricitinib | BARICITINIB | IC50 | = | 149 | nM | ALA3299206 | 6.83 | nM | Homo sapiens | ||
10. | Baricitinib | BARICITINIB | IC50 | = | 81.9 | nM | ALA3299208 | 7.09 | nM | Homo sapiens | ||
11. | TYK2 inhibitor 14l | 14l | INH | 0 | ALA4825803 | Active | % | Homo sapiens | ||||
12. | TYK2 inhibitor 14l | 14l | fIC50 | = | 189.2 | nM | ALA4825799 | nM | Homo sapiens | |||
13. | TYK2 inhibitor 14l | 14l | fIC50 | = | 14.5 | nM | ALA4825798 | nM | Homo sapiens | |||
14. | TYK2 inhibitor 14l | 14l | IC50 | = | 652.4 | nM | ALA4825794 | 6.18 | nM | Homo sapiens | ||
15. | TYK2 inhibitor 14l | 14l | IC50 | = | 49.9 | nM | ALA4825793 | 7.30 | nM | Homo sapiens | ||
16. | ALA3655081 | ABROCITINIB | IC50 | > | 16.452 | uM | ALA4023014 | nM | Homo sapiens | |||
17. | ALA3655081 | ABROCITINIB | IC50 | = | 13.673 | uM | ALA4023013 | 4.86 | nM | Homo sapiens | ||
18. | ALA4531793 | 42 | IC50 | = | 1.1 | uM | ALA4414789 | 5.96 | nM | Homo sapiens | ||
19. | ALA4542289 | 41 | IC50 | = | 2 | uM | ALA4414789 | 5.70 | nM | Homo sapiens | ||
20. | ALA4438202 | 40 | IC50 | = | 0.43 | uM | ALA4414789 | 6.37 | nM | Homo sapiens |