| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  SOS1 PROTAC 9d | 9d | Kd | = | 56 | nM | ALA5160171 | 7.25 | nM | Homo sapiens | ||
| 2. |  6-Chlorothiochroman-4-one | MB1200 | Kd | = | 6.7 | nM | ALA4234785 | 8.17 | nM | Homo sapiens | ||
| 3. |  [4-(1H-Pyrrol-1-yl)phenyl]methanol | MB756 | Kd | = | 5 | nM | ALA4234785 | 8.30 | nM | Homo sapiens | ||
| 4. |  ALA4247887 | MB235 | deltaTm | > | 0.5 | degrees C | ALA4234787 | degrees C | Homo sapiens | |||
| 5. | 6-Chlorothiochroman-4-one | MB1200 | deltaTm | > | 0.5 | degrees C | ALA4234787 | degrees C | Homo sapiens | |||
| 6. | [4-(1H-Pyrrol-1-yl)phenyl]methanol | MB756 | deltaTm | > | 0.5 | degrees C | ALA4234787 | degrees C | Homo sapiens | |||
| 7. |  ALA4224723 | 4 | Kd | = | 21.6 | uM | ALA4223599 | 4.67 | nM | Homo sapiens | ||
| 8. |  ALA4228750 | 3 | Kd | = | 0.76 | uM | ALA4223599 | 6.12 | nM | Homo sapiens | ||
| 9. |  ALA4225198 | 2 | Kd | = | 9.4 | uM | ALA4223599 | 5.03 | nM | Homo sapiens | ||
| 10. |  ALA4227864 | 11 | Kd | = | 0.44 | uM | ALA4223599 | 6.36 | nM | Homo sapiens | ||
| 11. | ALA4224723 | 4 | Kd | > | 13 | uM | ALA4223598 | nM | Homo sapiens | |||
| 12. | ALA4228750 | 3 | Kd | = | 1 | uM | ALA4223598 | 6.00 | nM | Homo sapiens | ||
| 13. | ALA4225198 | 2 | Kd | = | 7.07 | uM | ALA4223598 | 5.15 | nM | Homo sapiens | ||
| 14. | ALA4227864 | 11 | Kd | = | 0.69 | uM | ALA4223598 | 6.16 | nM | Homo sapiens | ||
| 15. |  ALA4225470 | 10 | INH | 0 | ALA4219880 | Active | % | Homo sapiens | ||||
| 16. |  ALA4229211 | 18 | t1/2 | = | 2.71 | s | ALA4219897 | hr | Homo sapiens | |||
| 17. |  ALA4228950 | 16 | t1/2 | = | 4.101 | s | ALA4219897 | hr | Homo sapiens | |||
| 18. |  VH 298 | 15; VH298 | t1/2 | = | 5.874 | s | ALA4219897 | hr | Homo sapiens | |||
| 19. | ALA4225470 | 10 | t1/2 | = | 7.073 | s | ALA4219897 | hr | Homo sapiens | |||
| 20. |  ALA3344081 | 7 | t1/2 | = | 2.98 | s | ALA4219897 | hr | Homo sapiens |
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