# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Miltefosine | Miltefosine | IC50 | = | 54.5 | uM | ALA4263296 | 4.26 | nM | Naegleria fowleri | ||
2. | Amphotericin B solution | amphotericin B | IC50 | = | 0.2 | uM | ALA4263296 | 6.70 | nM | Naegleria fowleri | ||
3. | ALA4278360 | 4p | IC50 | = | 27.3 | uM | ALA4263296 | 4.56 | nM | Naegleria fowleri | ||
4. | ALA4278038 | 4j | IC50 | = | 14.8 | uM | ALA4263296 | 4.83 | nM | Naegleria fowleri | ||
5. | ALA4276974 | 4g | IC50 | = | 28.3 | uM | ALA4263296 | 4.55 | nM | Naegleria fowleri | ||
6. | ALA1760526 | 6c | IC50 | = | 14.5 | uM | ALA4263296 | 4.84 | nM | Naegleria fowleri | ||
7. | 1-(2-bromoethyl)-1H-indole-2,3-dione | 5 | IC50 | = | 23.6 | uM | ALA4263296 | 4.63 | nM | Naegleria fowleri | ||
8. | ALA4160092 | 7 | Activity | 0 | ALA4136738 | Not Active | Naegleria fowleri | |||||
9. | ALA518246 | 6 | Activity | 0 | ALA4136738 | Not Active | Naegleria fowleri | |||||
10. | ALA4175220 | 5 | Activity | 0 | ALA4136738 | Not Active | Naegleria fowleri | |||||
11. | ALA4161167 | 4 | Activity | 0 | ALA4136738 | Not Active | Naegleria fowleri | |||||
12. | ALA4171774 | 3 | Activity | 0 | ALA4136738 | Not Active | Naegleria fowleri | |||||
13. | ALA4176274 | 2 | Activity | 0 | ALA4136738 | Not Active | Naegleria fowleri | |||||
14. | ALA4168409 | 1 | Activity | 0 | ALA4136738 | Not Active | Naegleria fowleri | |||||
15. | Chlorpromazine | cholrpromazine | Time | = | 17.2 | day | ALA1284797 | hr | Naegleria fowleri | |||
16. | Amphotericin B solution | amphotericin B | Activity | 0 | ALA1284798 | Active | Naegleria fowleri | |||||
17. | Miltefosine | Miltefosine | Activity | 0 | ALA1284798 | Active | Naegleria fowleri | |||||
18. | Chlorpromazine | cholrpromazine | Activity | 0 | ALA1284798 | Active | Naegleria fowleri | |||||
19. | Chlorpromazine | cholrpromazine | MIC100 | = | 12.5 | ug ml-1 | ALA1283873 | ug ml-1 | Naegleria fowleri | |||
20. | Chlorpromazine | cholrpromazine | MIC100 | = | 12.5 | ug ml-1 | ALA1283875 | ug ml-1 | Naegleria fowleri |