# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5173331 | 4b | t1/2 | = | 56 | min | ALA5163566 | hr | Rattus norvegicus | |||
2. | Tolvaptan | 4 | t1/2 | = | 23 | min | ALA5163566 | hr | Rattus norvegicus | |||
3. | ALA4468523 | 38 | Efficacy | = | 99 | % | ALA4397513 | % | Rattus norvegicus | |||
4. | ALA4539370 | 19 | Efficacy | = | 91 | % | ALA4397513 | % | Rattus norvegicus | |||
5. | Desmopressin | dDAVP | Efficacy | = | 100 | % | ALA4397513 | % | Rattus norvegicus | |||
6. | ALA4468523 | 38 | EC50 | = | 0.02 | nM | ALA4397512 | 10.70 | nM | Rattus norvegicus | ||
7. | ALA4539370 | 19 | EC50 | = | 0.05 | nM | ALA4397512 | 10.30 | nM | Rattus norvegicus | ||
8. | Desmopressin | dDAVP | EC50 | = | 0.03 | nM | ALA4397512 | 10.52 | nM | Rattus norvegicus | ||
9. | conivaptan | Conivaptan | Ki | = | 3.04 | nM | ALA4201578 | 8.52 | nM | Rattus norvegicus | ||
10. | L-368,899 hydrochloride | 5 | IC50 | = | 570 | nM | ALA2394480 | 6.24 | nM | Rattus norvegicus | ||
11. | ALA2391300 | 1 | IC50 | = | 350 | nM | ALA2394480 | 6.46 | nM | Rattus norvegicus | ||
12. | ALA1253499 | 13, SSR-126768A | Ki | > | 1000 | nM | ALA1253122 | nM | Rattus norvegicus | |||
13. | L-372662 | 30 | Ki | = | 9700 | nM | ALA1253105 | 5.01 | nM | Rattus norvegicus | ||
14. | L-371,257 | 1 | Ki | > | 30000 | nM | ALA1253105 | nM | Rattus norvegicus | |||
15. | OPC 21268 | OPC-21268 | Ki | > | 30000 | nM | ALA1253105 | nM | Rattus norvegicus | |||
16. | L-368,899 hydrochloride | 5 | Ki | = | 200 | nM | ALA1253105 | 6.70 | nM | Rattus norvegicus | ||
17. | ALA341339 | 1 | Ki | = | 29000 | nM | ALA1253105 | 4.54 | nM | Rattus norvegicus | ||
18. | ALA341490 | 11 | Ki | > | 40000 | nM | ALA1253105 | nM | Rattus norvegicus | |||
19. | ALA182852 | 1 | EC50 | = | 50 | nM | ALA1015250 | 7.30 | nM | Rattus norvegicus | ||
20. | Fedovapagon | 20e, VA106483 | EC50 | = | 150 | nM | ALA1015250 | 6.82 | nM | Rattus norvegicus |