| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  Loratadine Epoxide | loratadine | IC50 | = | 4 | uM | ALA3386947 | 5.40 | nM | Homo sapiens | ||
| 2. |  ALA3357021 | 4-cyanoloratadine | IC50 | > | 80 | uM | ALA3386947 | nM | Homo sapiens | |||
| 3. |  4-Hydroxymethyl Loratadine | 4-(hydroxymethyl)loratadine | IC50 | = | 18.3 | uM | ALA3386947 | 4.74 | nM | Homo sapiens | ||
| 4. |  ALA3357023 | 3-hydroxyloratadine | IC50 | = | 17.6 | uM | ALA3386947 | 4.75 | nM | Homo sapiens | ||
| 5. |  ALA3357024 | 3-methoxyloratadine | IC50 | = | 4.5 | uM | ALA3386947 | 5.35 | nM | Homo sapiens | ||
| 6. |  ALA3357025 | 2-cyanoloratadine | IC50 | > | 80 | uM | ALA3386947 | nM | Homo sapiens | |||
| 7. |  2-Hydroxymethyl Loratadine | 2-(hydroxymethyl)loratadine | IC50 | > | 80 | uM | ALA3386947 | nM | Homo sapiens | |||
| 8. |  ALA3357029 | 3 | IC50 | = | 5.3 | uM | ALA3386947 | 5.28 | nM | Homo sapiens | ||
| 9. |  ALA331603 | 1g | IC50 | = | 4.9 | uM | ALA3386947 | 5.31 | nM | Homo sapiens | ||
| 10. |  Iso Loratadine | isoloratadine | IC50 | = | 14.8 | uM | ALA3386947 | 4.83 | nM | Homo sapiens | ||
| 11. |  ALA3357027 | 2-(methoxycarbonyl)loratadine | IC50 | = | 12.4 | uM | ALA3386947 | 4.91 | nM | Homo sapiens | ||
| 12. |  ALA3357030 | 4 | IC50 | = | 35 | uM | ALA3386947 | 4.46 | nM | Homo sapiens | ||
| 13. |  ALA3357031 | 5 | IC50 | > | 80 | uM | ALA3386947 | nM | Homo sapiens | |||
| 14. |  8-Chloroazatadine | 1b | IC50 | > | 80 | uM | ALA3386947 | nM | Homo sapiens | |||
| 15. |  Desloratadine | 1a | IC50 | = | 172 | uM | ALA3386947 | nM | Homo sapiens | |||
| 16. |  rupatadine | 19 | IC50 | > | 40 | uM | ALA3386947 | nM | Homo sapiens | |||
| 17. |  ALA3357032 | 7 | IC50 | = | 19.6 | uM | ALA3386947 | 4.71 | nM | Homo sapiens | ||
| 18. |  ALA3357033 | 8 | IC50 | = | 4.6 | uM | ALA3386947 | 5.34 | nM | Homo sapiens | ||
| 19. |  ALA3357034 | 9 | IC50 | = | 16.8 | uM | ALA3386947 | 4.78 | nM | Homo sapiens | ||
| 20. |  ALA3357035 | 10 | IC50 | = | 7.8 | uM | ALA3386947 | 5.11 | nM | Homo sapiens |
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