Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	talazoparib	TALAZOPARIB	EC50	=	2.5	nM	ALA3429727	8.60		nM	Homo sapiens
2.	MK-4827 (Niraparib)	56, MK-4827	INH	>	50	%	ALA3429726			%	Homo sapiens
3.	MK-4827 (Niraparib)	56, MK-4827	INH	>	90	%	ALA3429725			%	Homo sapiens
4.	MK-4827 (Niraparib)	56, MK-4827	INH	>	90	%	ALA3429724			%	Homo sapiens
5.	MK-4827 (Niraparib)	56, MK-4827	IC90	=	50	nM	ALA3429595			nM	Homo sapiens
6.	MK-4827 (Niraparib)	56, MK-4827	IC50	=	3.5	nM	ALA3429595	8.46		nM	Homo sapiens
7.	MK-4827 (Niraparib)	56, MK-4827	IC90	=	52	nM	ALA3429594			nM	Homo sapiens
8.	MK-4827 (Niraparib)	56, MK-4827	IC50	=	4	nM	ALA3429594	8.40		nM	Homo sapiens
9.	ALA594298	5, PARP-1	EC50	=	3700	nM	ALA3428886	5.43		nM	Homo sapiens
10.	ALA1096641	37	EC50	=	110	nM	ALA3428886	6.96		nM	Homo sapiens
11.	ALA609862	6	EC50	=	68	nM	ALA3428886	7.17		nM	Homo sapiens
12.	ALA1094961	50	EC50	=	110	nM	ALA3428886	6.96		nM	Homo sapiens
13.	ALA1098296	14	EC50	=	13	nM	ALA3428886	7.89		nM	Homo sapiens
14.	ALA1098297	15	EC50	=	31	nM	ALA3428886	7.51		nM	Homo sapiens
15.	2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide	16	EC50	=	24	nM	ALA3428886	7.62		nM	Homo sapiens
16.	Niraparib (R-enantiomer)	57	EC50	=	30	nM	ALA3428886	7.52		nM	Homo sapiens
17.	MK-4827 (Niraparib)	56, MK-4827	EC50	=	4	nM	ALA3428886	8.40		nM	Homo sapiens
18.	MK-4827 (Niraparib)	56, MK-4827	IC90	=	46	nM	ALA3428886			nM	Homo sapiens
19.	Benzamide	28	INH		0		ALA1814971		Active	%	Homo sapiens
20.	ALA97945	19	INH		0		ALA1814971		Active	%	Homo sapiens