# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1236677 | VNI | IC50 | = | 0.25 | uM | ALA4125300 | 6.60 | nM | Aspergillus | ||
2. | Voriconazole | Voriconazole | Kd(app) | = | 56 | nM | ALA4125284 | 7.25 | nM | Aspergillus | ||
3. | Posaconazole | (S,S)-5 | Kd(app) | = | 131 | nM | ALA4125284 | 6.88 | nM | Aspergillus | ||
4. | ALA4126063 | 15 | Kd(app) | = | 132 | nM | ALA4125284 | 6.88 | nM | Aspergillus | ||
5. | ALA4128615 | 11 | Kd(app) | = | 61 | nM | ALA4125284 | 7.21 | nM | Aspergillus | ||
6. | ALA4128885 | 3 | Kd(app) | = | 20 | nM | ALA4125284 | 7.70 | nM | Aspergillus | ||
7. | ALA4127493 | 2 | Kd(app) | = | 55 | nM | ALA4125284 | 7.26 | nM | Aspergillus | ||
8. | ALA4129161 | 1 | Kd(app) | = | 57 | nM | ALA4125284 | 7.24 | nM | Aspergillus | ||
9. | ALA1236677 | VNI | Kd(app) | = | 203 | nM | ALA4125284 | 6.69 | nM | Aspergillus | ||
10. | Posaconazole | (S,S)-5 | INH | = | 93 | % | ALA4125281 | % | Aspergillus | |||
11. | ALA4126063 | 15 | INH | = | 57 | % | ALA4125281 | % | Aspergillus | |||
12. | ALA4127446 | 14 | INH | = | 32 | % | ALA4125281 | % | Aspergillus | |||
13. | ALA4127305 | 13 | INH | = | 24 | % | ALA4125281 | % | Aspergillus | |||
14. | ALA4128691 | 12 | INH | = | 26 | % | ALA4125281 | % | Aspergillus | |||
15. | ALA4128615 | 11 | INH | = | 80 | % | ALA4125281 | % | Aspergillus | |||
16. | ALA4127234 | 10 | INH | = | 23 | % | ALA4125281 | % | Aspergillus | |||
17. | ALA4127633 | 9 | INH | = | 34 | % | ALA4125281 | % | Aspergillus | |||
18. | ALA4126258 | 8 | INH | = | 3 | % | ALA4125281 | % | Aspergillus | |||
19. | ALA4126409 | 7 | INH | = | 15 | % | ALA4125281 | % | Aspergillus | |||
20. | ALA4129699 | 6 | INH | = | 41 | % | ALA4125281 | % | Aspergillus |