| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3403768 | 6 | Ratio | = | 3.1 | ALA5240737 | Homo sapiens | |||||
| 2. |  ALA3403780 | 19 | Ratio | = | 0.7 | ALA5240737 | Homo sapiens | |||||
| 3. |  ALA5285428 | (S,S)-2-PCCA | Ratio | = | 0.3 | ALA5240737 | Homo sapiens | |||||
| 4. |  (1R,2R)-N-[(2S,3S)-2-amino-3-methylpentyl]-N-[4-(4-propylphenyl)phenyl]-2-pyridin-2-ylcyclopropane-1-carboxamide | 129 | Ratio | = | 3.7 | ALA5240737 | Homo sapiens | |||||
| 5. |  RTI-13951-33 | RTI-13951-33 | Ratio | = | 5 | ALA5240737 | Homo sapiens | |||||
| 6. | ALA3403768 | 6 | Ki | = | 612 | nM | ALA5240736 | 6.21 | nM | Homo sapiens | ||
| 7. | ALA3403780 | 19 | Ki | = | 219 | nM | ALA5240736 | 6.66 | nM | Homo sapiens | ||
| 8. | ALA5285428 | (S,S)-2-PCCA | Ki | = | 487 | nM | ALA5240736 | 6.31 | nM | Homo sapiens | ||
| 9. | (1R,2R)-N-[(2S,3S)-2-amino-3-methylpentyl]-N-[4-(4-propylphenyl)phenyl]-2-pyridin-2-ylcyclopropane-1-carboxamide | 129 | Ki | = | 277 | nM | ALA5240736 | 6.56 | nM | Homo sapiens | ||
| 10. | RTI-13951-33 | RTI-13951-33 | Ki | = | 224 | nM | ALA5240736 | 6.65 | nM | Homo sapiens | ||
| 11. | ALA3403768 | 6 | EC50 | = | 195 | nM | ALA5240735 | 6.71 | nM | Homo sapiens | ||
| 12. | ALA3403780 | 19 | EC50 | = | 304 | nM | ALA5240735 | 6.52 | nM | Homo sapiens | ||
| 13. | ALA5285428 | (S,S)-2-PCCA | EC50 | = | 1738 | nM | ALA5240735 | 5.76 | nM | Homo sapiens | ||
| 14. | (1R,2R)-N-[(2S,3S)-2-amino-3-methylpentyl]-N-[4-(4-propylphenyl)phenyl]-2-pyridin-2-ylcyclopropane-1-carboxamide | 129 | EC50 | = | 74 | nM | ALA5240735 | 7.13 | nM | Homo sapiens | ||
| 15. | RTI-13951-33 | RTI-13951-33 | EC50 | = | 45 | nM | ALA5240735 | 7.35 | nM | Homo sapiens | ||
| 16. |  ALA5276110 | 7; [3H]RTI-33 | Bmax | = | 4.5 | pmol/mg | ALA5240734 | pmol/mg | Homo sapiens | |||
| 17. | ALA5276110 | 7; [3H]RTI-33 | Kd | = | 85 | nM | ALA5240734 | 7.07 | nM | Homo sapiens | ||
| 18. | (1R,2R)-N-[(2S,3S)-2-amino-3-methylpentyl]-N-[4-(4-propylphenyl)phenyl]-2-pyridin-2-ylcyclopropane-1-carboxamide | 129 | EC50 | = | 73 | nM | ALA5132114 | 7.14 | nM | Homo sapiens | ||
| 19. |  ALA5175064 | 53 | Ratio EC50 | = | 3 | ALA5132105 | Homo sapiens | |||||
| 20. | ALA5175064 | 53 | Emax | = | 92 | % | ALA5132101 | % | Homo sapiens |
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