# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Lenvatinib (E7080) | E7080 | IC50 | = | 10 | nM | ALA3428796 | 8.00 | nM | Homo sapiens | ||
2. | methyl (4-(4-amino-5-(5-amino-4-chloro-2-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)bicyclo[ 2.2.2]octan-1-yl)carbamate | 1 | IC50 | = | 0.022 | uM | ALA4834259 | 7.66 | nM | Homo sapiens | ||
3. | ALA4857808 | 12 | IC50 | = | 0.02 | uM | ALA4834259 | 7.70 | nM | Homo sapiens | ||
4. | ALA4874648 | 11 | IC50 | = | 0.015 | uM | ALA4834259 | 7.82 | nM | Homo sapiens | ||
5. | ALA4877264 | 10 | IC50 | = | 0.044 | uM | ALA4834259 | 7.36 | nM | Homo sapiens | ||
6. | ALA4860822 | 9 | IC50 | = | 3 | uM | ALA4834259 | 5.52 | nM | Homo sapiens | ||
7. | ALA4853155 | 8 | IC50 | = | 0.09 | uM | ALA4834259 | 7.05 | nM | Homo sapiens | ||
8. | ALA4855562 | 7 | IC50 | = | 1.9 | uM | ALA4834259 | 5.72 | nM | Homo sapiens | ||
9. | ALA4864386 | 6 | IC50 | = | 2.8 | uM | ALA4834259 | 5.55 | nM | Homo sapiens | ||
10. | ALA4848347 | 5 | IC50 | = | 0.77 | uM | ALA4834259 | 6.11 | nM | Homo sapiens | ||
11. | ALA4854822 | 4 | IC50 | = | 0.24 | uM | ALA4834259 | 6.62 | nM | Homo sapiens | ||
12. | ALA169390 | 13e | IC50 | = | 0.007 | uM | ALA4834259 | 8.15 | nM | Homo sapiens | ||
13. | ALA4858720 | 2 | IC50 | = | 0.011 | uM | ALA4834259 | 7.96 | nM | Homo sapiens | ||
14. | ALA4790634 | 9x | INH | 0 | ALA4710010 | Dose-dependent effect | % | Homo sapiens | ||||
15. | ALA4790634 | 9x | INH | 0 | ALA4710008 | Dose-dependent effect | % | Homo sapiens | ||||
16. | Staurosporine (DMSO solution) | 1 (Staurosporine) | IC50 | = | 1.51 | nM | ALA4709993 | 8.82 | nM | Homo sapiens | ||
17. | ALA4790634 | 9x | IC50 | = | 8.86 | nM | ALA4709993 | 8.05 | nM | Homo sapiens | ||
18. | ALA4757026 | 9l | Survival | = | 74.89 | % | ALA4709984 | % | Homo sapiens | |||
19. | ALA4742253 | 9k | Survival | = | 56.49 | % | ALA4709984 | % | Homo sapiens | |||
20. | ALA4751021 | 9g | Survival | = | 87.5 | % | ALA4709984 | % | Homo sapiens |