# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Lenvatinib (E7080) | E7080 | IC50 | = | 10 | nM | ALA3428924 | 8.00 | nM | Homo sapiens | ||
2. | methyl (4-(4-amino-5-(5-amino-4-chloro-2-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)bicyclo[ 2.2.2]octan-1-yl)carbamate | 1 | IC50 | = | 0.051 | uM | ALA4834316 | 7.29 | nM | Homo sapiens | ||
3. | ALA4857808 | 12 | IC50 | = | 0.11 | uM | ALA4834316 | 6.96 | nM | Homo sapiens | ||
4. | ALA4874648 | 11 | IC50 | = | 0.035 | uM | ALA4834316 | 7.46 | nM | Homo sapiens | ||
5. | ALA4877264 | 10 | IC50 | = | 0.046 | uM | ALA4834316 | 7.34 | nM | Homo sapiens | ||
6. | ALA4790634 | 9x | INH | 0 | ALA4710017 | Active | % | Homo sapiens | ||||
7. | ALA4790634 | 9x | INH | 0 | ALA4710016 | Active | % | Homo sapiens | ||||
8. | ALA4790634 | 9x | INH | 0 | ALA4710015 | Active | % | Homo sapiens | ||||
9. | ALA4790634 | 9x | INH | 0 | ALA4710014 | Active | % | Homo sapiens | ||||
10. | ALA4790634 | 9x | GI50 | = | 0.038 | uM | ALA4709997 | nM | Homo sapiens | |||
11. | Staurosporine (DMSO solution) | 1 (Staurosporine) | IC50 | = | 2.22 | nM | ALA4709992 | 8.65 | nM | Homo sapiens | ||
12. | ALA4790634 | 9x | IC50 | = | 5.43 | nM | ALA4709992 | 8.27 | nM | Homo sapiens | ||
13. | ALA4757026 | 9l | Survival | = | 94.12 | % | ALA4709983 | % | Homo sapiens | |||
14. | ALA4742253 | 9k | Survival | = | 65.47 | % | ALA4709983 | % | Homo sapiens | |||
15. | ALA4751021 | 9g | Survival | = | 100.2 | % | ALA4709983 | % | Homo sapiens | |||
16. | ALA4582651 | PRALSETINIB | GI50 | < | 0.004 | uM | ALA4709981 | nM | Homo sapiens | |||
17. | Cabozantinib (XL184, BMS-907351) | CABOZANTINIB | GI50 | = | 0.029 | uM | ALA4709981 | nM | Homo sapiens | |||
18. | ALA4743094 | 20n | GI50 | = | 0.079 | uM | ALA4709981 | nM | Homo sapiens | |||
19. | ALA4748770 | 20m | GI50 | = | 0.342 | uM | ALA4709981 | nM | Homo sapiens | |||
20. | ALA4791776 | 20l | GI50 | = | 0.013 | uM | ALA4709981 | nM | Homo sapiens |