| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  HET-0016 | 3a (HET0016) | IC50 | = | 155.3 | nM | ALA5238695 | 6.81 | nM | Homo sapiens | ||
| 2. |  ALA5272822 | 7c | IC50 | = | 1598.3 | nM | ALA5238695 | 5.80 | nM | Homo sapiens | ||
| 3. |  8-(benzotriazol-1-ylamino)octanoic acid | 7 | Ratio IC50 | = | 2.9 | ALA4406443 | Homo sapiens | |||||
| 4. |  ALA4442292 | 6 | Ratio IC50 | = | 1.5 | ALA4406443 | Homo sapiens | |||||
| 5. | 8-(benzotriazol-1-ylamino)octanoic acid | 7 | IC50 | = | 57 | uM | ALA4406438 | 4.24 | nM | Homo sapiens | ||
| 6. | ALA4442292 | 6 | IC50 | = | 778 | uM | ALA4406438 | nM | Homo sapiens | |||
| 7. | 8-(benzotriazol-1-ylamino)octanoic acid | 7 | IC50 | = | 167 | uM | ALA4406432 | nM | Homo sapiens | |||
| 8. | ALA4442292 | 6 | IC50 | = | 1180 | uM | ALA4406432 | nM | Homo sapiens | |||
| 9. |  ALA4435658 | 9 | INH | 0 | ALA4406425 | Active | % | Homo sapiens | ||||
| 10. |  ALA4590991 | 8 | INH | 0 | ALA4406425 | Active | % | Homo sapiens | ||||
| 11. | 8-(benzotriazol-1-ylamino)octanoic acid | 7 | INH | 0 | ALA4406425 | Active | % | Homo sapiens | ||||
| 12. | ALA4442292 | 6 | INH | 0 | ALA4406425 | Active | % | Homo sapiens | ||||
| 13. |  ALA4554028 | 5 | INH | 0 | ALA4406425 | Active | % | Homo sapiens | ||||
| 14. |  ALA4466562 | 4 | INH | 0 | ALA4406425 | Active | % | Homo sapiens | ||||
| 15. |  ALA4447108 | 3 | INH | 0 | ALA4406425 | Active | % | Homo sapiens | ||||
| 16. |  ALA4564920 | 2 | INH | 0 | ALA4406425 | Active | % | Homo sapiens | ||||
| 17. |  ALA3542381 | M20 | Drug metabolism | 0 | ALA3531668 | metabolite_detected | Homo sapiens | |||||
| 18. |  ALA3542336 | [14C]-SCH 530348 | Drug metabolism | 0 | ALA3531396 | metabolite_detected | Homo sapiens | |||||
| 19. |  ALA3527528 | M15 | Compound recovery | = | 1.19 | % | ALA3532909 | % | Homo sapiens | |||
| 20. |  ALA3526818 | [14C]-Fingolimod, FTY720 | Drug metabolism | 0 | ALA3535849 | metabolite_not_detected | Homo sapiens |
The page will load shortly, Thanks for your patience!