# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Pexidartinib | PEXIDARTINIB | IC50 | = | 670 | nM | ALA5238341 | 6.17 | nM | Homo sapiens | ||
2. | ALA5284731 | HSN431 | IC50 | = | 0.5 | nM | ALA5230537 | 9.30 | nM | Homo sapiens | ||
3. | CHMFL-FLT3-122 | 18; CHMFL-FLT3-122 | GI50 | = | 42 | nM | ALA5230521 | nM | Homo sapiens | |||
4. | FF-10101 | FF-10101 | GI50 | = | 1.5 | nM | ALA5230521 | nM | Homo sapiens | |||
5. | UNC2025 | 11, UNC2025 | IC50 | = | 14 | nM | ALA5230510 | 7.85 | nM | Homo sapiens | ||
6. | Crenolanib (CP-868596) | CRENOLANIB | IC50 | = | 2 | nM | ALA5230510 | 8.70 | nM | Homo sapiens | ||
7. | G-749 | G-749 | IC50 | = | 7.5 | nM | ALA5230509 | 8.12 | nM | Homo sapiens | ||
8. | ALA5269280 | HSN286 | IC50 | = | 0.72 | nM | ALA5230509 | 9.14 | nM | Homo sapiens | ||
9. | Gilteritinib | GILTERITINIB | IC50 | = | 1.8 | nM | ALA5230509 | 8.74 | nM | Homo sapiens | ||
10. | Tandutinib (MLN518) | 75 | IC50 | = | 10 | nM | ALA5230509 | 8.00 | nM | Homo sapiens | ||
11. | Crenolanib (CP-868596) | CRENOLANIB | IC50 | = | 2 | nM | ALA5230509 | 8.70 | nM | Homo sapiens | ||
12. | ALA5284152 | 8j; FF-10101 | GI50 | = | 1.5 | nM | ALA5224528 | nM | Homo sapiens | |||
13. | ALA5284120 | 75; RC-1 | IC50 | = | 0.3 | uM | ALA5224336 | 6.52 | nM | Homo sapiens | ||
14. | RG7388 | 12, RG7388 | INH | = | 40 | % | ALA5223982 | % | Homo sapiens | |||
15. | ALA5286157 | 15 | INH | > | 90 | % | ALA5223982 | % | Homo sapiens | |||
16. | Pexidartinib | PEXIDARTINIB | IC50 | = | 670 | nM | ALA5150812 | 6.17 | nM | Homo sapiens | ||
17. | ALA5170277 | 10; MZH29 | IC50 | = | 0.13 | nM | ALA5150811 | 9.89 | nM | Homo sapiens | ||
18. | Pexidartinib | PEXIDARTINIB | IC50 | = | 350 | nM | ALA5150811 | 6.46 | nM | Homo sapiens | ||
19. | ALA4555872 | 15; FLT-3 PROTAC | IC50 | = | 0.6 | nM | ALA5137709 | 9.22 | nM | Homo sapiens | ||
20. | ASLAN003 | 6 | IC50 | = | 582 | nM | ALA5128093 | 6.24 | nM | Homo sapiens |