# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3699142 | BDBM142744 | IC50 | = | 4 | nM | ALA5246062 | 8.40 | nM | Homo sapiens | ||
2. | ALA5280597 | P6b | DC50 | = | 0.2 | uM | ALA5225718 | uM | Homo sapiens | |||
3. | ALA1614701 | AZD-6244 | Kd | = | 530 | nM | ALA5213094 | 6.28 | nM | Homo sapiens | ||
4. | Cobimetinib | 1, XL518, GDC-0973 | IC50 | = | 23 | nM | ALA5213149 | 7.64 | nM | Homo sapiens | ||
5. | PD0325901 | 34, PD-0325901 | IC50 | = | 110 | nM | ALA5210367 | 6.96 | nM | Homo sapiens | ||
6. | ALA1614701 | AZD-6244 | Kd | = | 530 | nM | ALA5210362 | 6.28 | nM | Homo sapiens | ||
7. | PD184352 (CI-1040) | 1 | Kd | = | 370 | nM | ALA5210630 | 6.43 | nM | Homo sapiens | ||
8. | PD0325901 | 34, PD-0325901 | IC50 | = | 14 | nM | ALA5209950 | 7.85 | nM | Homo sapiens | ||
9. | U0126 | U-0126 | IC50 | = | 58 | nM | ALA5131974 | 7.24 | nM | Homo sapiens | ||
10. | PD184352 (CI-1040) | 1 | IC50 | = | 17 | nM | ALA5131723 | 7.77 | nM | Homo sapiens | ||
11. | Trametinib (GSK1120212) | TRAMETINIB | IC50 | = | 1.8 | nM | ALA5131723 | 8.74 | nM | Homo sapiens | ||
12. | U0126 | U-0126 | IC50 | = | 58 | nM | ALA5131723 | 7.24 | nM | Homo sapiens | ||
13. | Trametinib (GSK1120212) | TRAMETINIB | IC50 | = | 1.8 | nM | ALA5131620 | 8.74 | nM | Homo sapiens | ||
14. | ALA5172852 | yn-1 | Activity | 0 | ALA5125986 | Active | Homo sapiens | |||||
15. | ALA5172852 | yn-1 | Activity | 0 | ALA5125979 | Active | Homo sapiens | |||||
16. | ALA5179338 | 1v | INH | 0 | ALA5117054 | NA | % | Homo sapiens | ||||
17. | ALA5182819 | 1k | INH | 0 | ALA5117054 | NA | % | Homo sapiens | ||||
18. | ALA5174740 | 1l | INH | = | 16.45 | % | ALA5115274 | % | Homo sapiens | |||
19. | ALA5189396 | 1k | INH | = | 17.33 | % | ALA5115274 | % | Homo sapiens | |||
20. | ALA5202188 | 1j | INH | = | 10.38 | % | ALA5115274 | % | Homo sapiens |