# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3290631 | 17a | Activity | = | 112 | % | ALA3292191 | % | Mus musculus | |||
2. | ALA3290628 | 13k | Activity | = | 113 | % | ALA3292191 | % | Mus musculus | |||
3. | TC-S 7001 | SID103905649 | % inhibition | -21 | % | ALA4881541 | Not Active | % | Mus musculus | |||
4. | 2,6-Dimethyl-4-(3-methyl-1H-indazol-5-yl)-1,4-dihydropyridine-3,5-dicarbonitrile(BAY-474) | EUB0000293 | % inhibition | 31 | % | ALA4880678 | Not Active | % | Mus musculus | |||
5. | ALA4857316 | 74 | Kd | = | 1.1 | nM | ALA4814587 | 8.96 | nM | Mus musculus | ||
6. | ALA4848804 | 73 | Kd | = | 0.85 | nM | ALA4814587 | 9.07 | nM | Mus musculus | ||
7. | ALA4868537 | 70 | Kd | = | 3.5 | nM | ALA4814587 | 8.46 | nM | Mus musculus | ||
8. | Vemurafenib (PLX4032, RG7204) | VEMURAFENIB | Kd | = | 8.2 | nM | ALA4814587 | 8.09 | nM | Mus musculus | ||
9. | ALA4857316 | 74 | Activity | = | 0.35 | % | ALA4814583 | % | Mus musculus | |||
10. | ALA4848804 | 73 | Activity | = | 0.2 | % | ALA4814583 | % | Mus musculus | |||
11. | ALA4868537 | 70 | Activity | = | 2.2 | % | ALA4814583 | % | Mus musculus | |||
12. | ALA4863128 | 69 | Activity | = | 2.9 | % | ALA4814583 | % | Mus musculus | |||
13. | ALA4872509 | 68 | Activity | = | 3.3 | % | ALA4814583 | % | Mus musculus | |||
14. | ALA4864124 | 67 | Activity | = | 2.4 | % | ALA4814583 | % | Mus musculus | |||
15. | ALA4874545 | 66 | Activity | = | 8.9 | % | ALA4814583 | % | Mus musculus | |||
16. | ALA4846221 | 65 | Activity | = | 28 | % | ALA4814583 | % | Mus musculus | |||
17. | ALA4858391 | 64 | Activity | = | 92 | % | ALA4814583 | % | Mus musculus | |||
18. | ALA4854287 | 63 | Activity | = | 78 | % | ALA4814583 | % | Mus musculus | |||
19. | ALA4850069 | 62 | Activity | = | 45 | % | ALA4814583 | % | Mus musculus | |||
20. | ALA4868690 | 61 | Activity | = | 100 | % | ALA4814583 | % | Mus musculus |