# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ML300 | 16e, ML300, SID 99289112 | INH | = | 75 | % | ALA2445668 | % | Homo sapiens | |||
2. | ALA2425785 | 9a | Activity | 0 | ALA2428731 | Active | Homo sapiens | |||||
3. | ALA2425782 | [11C]9a | Activity | 0 | ALA2428731 | Active | Homo sapiens | |||||
4. | [³H]melatonin | 1 | IC50 | = | 4.4 | 10'-10M | ALA2395686 | 9.36 | nM | Homo sapiens | ||
5. | [³H]melatonin | 1 | Ki | = | 3.5 | 10'-10M | ALA2395686 | 9.46 | nM | Homo sapiens | ||
6. | E1R | E1R, 4R,5S-2a | INH | = | -6 | % | ALA2395979 | % | Homo sapiens | |||
7. | [³H]melatonin | 1 | IC50 | = | 0.53 | nM | ALA2395007 | 9.28 | nM | Homo sapiens | ||
8. | ALA2392692 | 27, GSK2188931B | INH | < | 50 | % | ALA2395852 | % | Homo sapiens | |||
9. | ALA2326501 | 5d | INH | = | -6 | % | ALA2329398 | % | Homo sapiens | |||
10. | [³H]melatonin | 1 | Ki | = | 0.296 | nM | ALA2328138 | 9.53 | nM | Homo sapiens | ||
11. | ALA2326199 | 1 | Ki | = | 121 | nM | ALA2328138 | 6.92 | nM | Homo sapiens | ||
12. | ALA2326200 | 7 | Ki | = | 38.2 | nM | ALA2328138 | 7.42 | nM | Homo sapiens | ||
13. | ALA2326201 | 8 | Ki | = | 22.2 | nM | ALA2328138 | 7.65 | nM | Homo sapiens | ||
14. | BOMPPA | 9 | Ki | = | 39.5 | nM | ALA2328138 | 7.40 | nM | Homo sapiens | ||
15. | ALA2326203 | 10 | Ki | = | 32.7 | nM | ALA2328138 | 7.49 | nM | Homo sapiens | ||
16. | ALA2326199 | 1 | EC50 | = | 9.03 | nM | ALA2328005 | 8.04 | nM | Homo sapiens | ||
17. | ALA2326200 | 7 | EC50 | = | 8.38 | nM | ALA2328005 | 8.08 | nM | Homo sapiens | ||
18. | ALA2326201 | 8 | EC50 | = | 16.3 | nM | ALA2328005 | 7.79 | nM | Homo sapiens | ||
19. | BOMPPA | 9 | EC50 | = | 41.6 | nM | ALA2328005 | 7.38 | nM | Homo sapiens | ||
20. | ALA2326203 | 10 | EC50 | = | 2.94 | nM | ALA2328005 | 8.53 | nM | Homo sapiens |