# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Caffeine | caffeine | pKi | = | 5 | ALA5223701 | 5.00 | nM | Homo sapiens | |||
2. | ALA2203870 | 1, enantiomeric mixture | IC50 | = | 5 | uM | ALA2213713 | 5.30 | nM | Homo sapiens | ||
3. | ALA1224660 | Table 1 R1C5 | Activity | = | 1.09 | uM | ALA1225626 | uM | Homo sapiens | |||
4. | 2,6-Diaminopurine | 2 | INH | 0 | ALA1225632 | Not Active | % | Homo sapiens | ||||
5. | 2,6-Dihydroxypurine | xanthine | INH | 0 | ALA1225632 | Not Active | % | Homo sapiens | ||||
6. | 7-Methylxanthine | 51 | INH | 0 | ALA1225632 | Active | % | Homo sapiens | ||||
7. | Uric acid | Urate | Ki | = | 4.34 | uM | ALA1225633 | 5.36 | nM | Homo sapiens | ||
8. | 7-Methylxanthine | 51 | Ki | = | 5.55 | uM | ALA1225633 | 5.26 | nM | Homo sapiens | ||
9. | 2,6-Dihydroxypurine | xanthine | Ki | = | 1.96 | uM | ALA1225633 | 5.71 | nM | Homo sapiens | ||
10. | 2,6-Diaminopurine | 2 | Ki | = | 1.88 | uM | ALA1225633 | 5.73 | nM | Homo sapiens | ||
11. | 2-Acetamido-6-hydroxypurine | N-2-Acetylguanine | Ki | = | 3.44 | uM | ALA1225633 | 5.46 | nM | Homo sapiens | ||
12. | 5-Amino-4-imidazolecarboxamide | NSC-7784, CAS 360-97-4 | Ki | = | 4.44 | uM | ALA1225633 | 5.35 | nM | Homo sapiens | ||
13. | Caffeine | caffeine | Ki | = | 10.2 | uM | ALA1225633 | 4.99 | nM | Homo sapiens | ||
14. | Guanine | guanine | Km | = | 11.21 | uM | ALA1225627 | nM | Homo sapiens | |||
15. | ALA1645489 | 10 | Ki | = | 16.7 | 10'-6M | ALA1648250 | 4.78 | nM | Homo sapiens | ||
16. | ALA220699 | 2 | Ki | = | 53.6 | uM | ALA855086 | 4.27 | nM | Homo sapiens | ||
17. | ALA374469 | 1 | Ki | = | 20.1 | uM | ALA855086 | 4.70 | nM | Homo sapiens | ||
18. | ALA95745 | 1 | Ki | = | 0 | M | ALA684344 | 4.53 | nM | Homo sapiens | ||
19. | ALA120006 | 1 | Ki | = | 0 | M | ALA684343 | nM | Homo sapiens |