# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | N,N,2-Trimethyl-5-nitrobenzenesulfonamide | BRL-50481 | IC50 | = | 62 | uM | ALA5227541 | 4.21 | nM | Homo sapiens | ||
2. | ALA4127641 | 3; PF-04677490 | INH | = | 90 | % | ALA5226634 | % | Homo sapiens | |||
3. | ALA4127641 | 3; PF-04677490 | INH | = | 90 | % | ALA5226633 | % | Homo sapiens | |||
4. | ALA4127641 | 3; PF-04677490 | INH | = | 90 | % | ALA5226632 | % | Homo sapiens | |||
5. | ALA4127641 | 3; PF-04677490 | INH | = | 90 | % | ALA5226631 | % | Homo sapiens | |||
6. | (R)-1-(tert-Butyl)-6-((1-(4-chlorophenyl)ethyl)amino)-5-(4-fluorobenzyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one | 3m | IC50 | = | 0.003 | uM | ALA5226626 | 8.54 | nM | Homo sapiens | ||
7. | ALA4640793 | 3i | IC50 | = | 0.002 | uM | ALA5226626 | 8.82 | nM | Homo sapiens | ||
8. | ALA4649493 | 2 | IC50 | = | 0.005 | uM | ALA5226626 | 8.33 | nM | Homo sapiens | ||
9. | ALA5183221 | 1d | INH | = | 42 | % | ALA5168609 | % | Homo sapiens | |||
10. | ALA5192887 | 1c | INH | = | 43 | % | ALA5168609 | % | Homo sapiens | |||
11. | ALA5170293 | 1b | INH | = | 25 | % | ALA5168609 | % | Homo sapiens | |||
12. | ALA5198190 | 1a | INH | = | 7 | % | ALA5168609 | % | Homo sapiens | |||
13. | Nifedipine | nefidipine | IC50 | > | 10000 | nM | ALA5168608 | nM | Homo sapiens | |||
14. | ALA5193756 | 2h | IC50 | = | 285 | nM | ALA5168608 | 6.54 | nM | Homo sapiens | ||
15. | ALA5180169 | 2g | IC50 | = | 10 | nM | ALA5168608 | 8.00 | nM | Homo sapiens | ||
16. | ALA5208410 | 2f | IC50 | = | 189 | nM | ALA5168608 | 6.72 | nM | Homo sapiens | ||
17. | ALA5178800 | 2e | IC50 | = | 178 | nM | ALA5168608 | 6.75 | nM | Homo sapiens | ||
18. | ALA5181197 | 2d | IC50 | = | 88 | nM | ALA5168608 | 7.06 | nM | Homo sapiens | ||
19. | ALA5199616 | 2c | IC50 | = | 194 | nM | ALA5168608 | 6.71 | nM | Homo sapiens | ||
20. | ALA5176107 | 2b | IC50 | = | 297 | nM | ALA5168608 | 6.53 | nM | Homo sapiens |