Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	(R)-N-(1-(3-Chloro-4′-fluoro-[1,1′-biphenyl]-4-yl)-2-(1H-imidazol-1-yl)ethyl)-4-(5-(3-fluoro-5-(5-fluoropyrimidin-4-yl)phenyl)-1,3,4-oxadiazol-2-yl)benzamide	10	Kd	=	0.09	uM	ALA4323740	7.05	nM	Homo sapiens
2.	ALA4435160	9	Kd	=	0.15	uM	ALA4323740	6.82	nM	Homo sapiens
3.	ALA4461447	8	Kd	=	0.02	uM	ALA4323740	7.70	nM	Homo sapiens
4.	ALA4439225	7	Kd	=	0.13	uM	ALA4323740	6.89	nM	Homo sapiens
5.	ALA4466288	6	Kd	=	2.5	uM	ALA4323740	5.60	nM	Homo sapiens
6.	(R)-N-(1-(3-Chloro-4′-fluoro-[1,1′-biphenyl]-4-yl)-2-(1H-imidazol-1-yl)ethyl)-4-(5-(3-fluoro-5-(5-fluoropyrimidin-4-yl)phenyl)-1,3,4-oxadiazol-2-yl)benzamide	10	IC50	<	1	uM	ALA4323745		nM	Homo sapiens
7.	ALA4435160	9	IC50	<	1	uM	ALA4323745		nM	Homo sapiens
8.	ALA4461447	8	IC50	=	4.4	uM	ALA4323745	5.36	nM	Homo sapiens
9.	ALA4439225	7	IC50	=	3.6	uM	ALA4323745	5.44	nM	Homo sapiens
10.	ALA4466288	6	IC50	=	19	uM	ALA4323745	4.72	nM	Homo sapiens
11.	ALA4444489	5	IC50	=	15	uM	ALA4323745	4.82	nM	Homo sapiens
12.	ALA4472919	4	IC50	>	25	uM	ALA4323745		nM	Homo sapiens
13.	ALA4452294	3	IC50	>	25	uM	ALA4323745		nM	Homo sapiens
14.	ALA4593688	2	IC50	>	25	uM	ALA4323745		nM	Homo sapiens
15.	ALA4458275	1	IC50	>	25	uM	ALA4323745		nM	Homo sapiens
16.	ALA4277680	VFV-Cl	IC50	=	5.9	uM	ALA4323745	5.23	nM	Homo sapiens
17.	ALA3629567	VFV	IC50	=	24.4	uM	ALA4323745	4.61	nM	Homo sapiens
18.	(R)-N-(1-(3-Chloro-4′-fluoro-[1,1′-biphenyl]-4-yl)-2-(1H-imidazol-1-yl)ethyl)-4-(5-(3-fluoro-5-(5-fluoropyrimidin-4-yl)phenyl)-1,3,4-oxadiazol-2-yl)benzamide	10	INH	=	98	%	ALA4323744		%	Homo sapiens
19.	ALA4435160	9	INH	=	95	%	ALA4323744		%	Homo sapiens
20.	ALA4461447	8	INH	=	82	%	ALA4323744		%	Homo sapiens