# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | PDE4 inhibitor 16 | 16 | IC50 | = | 3.3 | uM | ALA4397916 | 5.48 | nM | Homo sapiens | ||
2. | Tadalafil | 2 | IC50 | = | 402 | nM | ALA4397441 | 6.40 | nM | Homo sapiens | ||
3. | Sildenafil | 1 | IC50 | = | 36.42 | nM | ALA4397441 | 7.44 | nM | Homo sapiens | ||
4. | ALA4462192 | 15; TPN171 | IC50 | = | 19.8 | nM | ALA4397441 | 7.70 | nM | Homo sapiens | ||
5. | BPN14770 | ZATOLMILAST | INH | 0 | ALA4397293 | Not Active | % | Homo sapiens | ||||
6. | Sildenafil Citrate | UK-92480, Sildenafil | INH | = | 85 | % | ALA4395211 | % | Homo sapiens | |||
7. | Sildenafil Citrate | UK-92480, Sildenafil | INH | = | 40 | % | ALA4395189 | % | Homo sapiens | |||
8. | Sildenafil Citrate | UK-92480, Sildenafil | INH | = | 8 | % | ALA4395167 | % | Homo sapiens | |||
9. | ALA4468513 | 3b; DRILS-1765 | INH | = | 2 | % | ALA4395108 | % | Homo sapiens | |||
10. | ALA4872902 | d12 | INH | = | 50 | % | ALA4808864 | % | Homo sapiens | |||
11. | ALA4879176 | d8 | IC50 | > | 10 | uM | ALA4808851 | nM | Homo sapiens | |||
12. | ALA4869439 | d4 | IC50 | > | 10 | uM | ALA4808851 | nM | Homo sapiens | |||
13. | ALA4852714 | d3 | IC50 | > | 10 | uM | ALA4808851 | nM | Homo sapiens | |||
14. | ALA4872902 | d12 | IC50 | > | 10 | uM | ALA4808851 | nM | Homo sapiens | |||
15. | ALA4861917 | c6 | IC50 | > | 10 | uM | ALA4808851 | nM | Homo sapiens | |||
16. | ALA4783529 | 11h | INH | < | 50 | % | ALA4730672 | % | Homo sapiens | |||
17. | (±)-Evodiamine | SID26756934 | EC50 | > | 20 | uM | ALA4729230 | nM | Homo sapiens | |||
18. | ALA4782533 | (S)-7b | EC50 | > | 20 | uM | ALA4729230 | nM | Homo sapiens | |||
19. | ALA2171791 | 14n | EC50 | > | 20 | uM | ALA4729230 | nM | Homo sapiens | |||
20. | ALA4794748 | (S)-7e | IC50 | > | 40 | uM | ALA4729230 | nM | Homo sapiens |