# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3699142 | BDBM142744 | IC50 | = | 25 | nM | ALA5246061 | 7.60 | nM | Homo sapiens | ||
2. | ALA5273533 | 37 | INH | = | 90 | % | ALA5244448 | % | Homo sapiens | |||
3. | ALA5281283 | 18 | IC50 | > | 1000 | nM | ALA5244447 | nM | Homo sapiens | |||
4. | ALA5288241 | B2 | INH | < | 50 | % | ALA5238263 | % | Homo sapiens | |||
5. | RO5126766 (CH5126766) | 1, CH5126766/RO5126766 | IC50 | = | 0.16 | uM | ALA5232570 | 6.80 | nM | Homo sapiens | ||
6. | ALA5286229 | 163b | IC50 | = | 0.98 | uM | ALA5232570 | 6.01 | nM | Homo sapiens | ||
7. | Debromohymenialdisine | 3 | IC50 | = | 0.82 | uM | ALA5227424 | 6.09 | nM | Homo sapiens | ||
8. | 10Z-Hymenialdisine | 1 (Hymenialdisine) | IC50 | = | 6 | nM | ALA5227424 | 8.22 | nM | Homo sapiens | ||
9. | Cobimetinib | 1, XL518, GDC-0973 | IC50 | = | 4.2 | uM | ALA5227207 | nM | Homo sapiens | |||
10. | ALA5280597 | P6b | DC50 | = | 0.3 | uM | ALA5225717 | uM | Homo sapiens | |||
11. | ALA1614701 | AZD-6244 | Kd | = | 99 | nM | ALA5213093 | 7.00 | nM | Homo sapiens | ||
12. | Cobimetinib | 1, XL518, GDC-0973 | IC50 | = | 31 | nM | ALA5213148 | 7.51 | nM | Homo sapiens | ||
13. | BI 2536 | 1 | % of control | = | 115 | % | ALA5213548 | % | Homo sapiens | |||
14. | Cobimetinib | 1, XL518, GDC-0973 | IC50 | = | 4.2 | nM | ALA5210383 | 8.38 | nM | Homo sapiens | ||
15. | PD0325901 | 34, PD-0325901 | IC50 | = | 82 | nM | ALA5210366 | 7.09 | nM | Homo sapiens | ||
16. | ALA1614701 | AZD-6244 | Kd | = | 99 | nM | ALA5210361 | 7.00 | nM | Homo sapiens | ||
17. | PD184352 (CI-1040) | 1 | Kd | = | 120 | nM | ALA5210629 | 6.92 | nM | Homo sapiens | ||
18. | PD0325901 | 34, PD-0325901 | IC50 | = | 0.33 | nM | ALA5210137 | 9.48 | nM | Homo sapiens | ||
19. | ALA1614701 | AZD-6244 | IC50 | = | 14 | nM | ALA5210136 | 7.85 | nM | Homo sapiens | ||
20. | PD184352 (CI-1040) | 1 | IC50 | = | 46 | nM | ALA5210306 | 7.34 | nM | Homo sapiens |