Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	(8R,9S)-Talazoparib	(8R,9S)-47	IC50	=	144	nM	ALA3767923	6.84	nM	Homo sapiens
2.	ALA3765670	(8R,9S)-57	IC50	=	5.6	nM	ALA3767923	8.25	nM	Homo sapiens
3.	ALA3764920	(8S,9R)-57	IC50	=	1.1	nM	ALA3767923	8.96	nM	Homo sapiens
4.	ALA3764624	(8R,9S)-46	IC50	=	68.9	nM	ALA3767923	7.16	nM	Homo sapiens
5.	ALA3763446	(8S,9R)-46	IC50	=	1.46	nM	ALA3767923	8.84	nM	Homo sapiens
6.	ALA3764202	(8S,9R)-42	IC50	=	1.6	nM	ALA3767923	8.80	nM	Homo sapiens
7.	ALA3764066	(8R,9S)-42	IC50	=	22.4	nM	ALA3767923	7.65	nM	Homo sapiens
8.	ALA3763822	(8S,9R)-36	IC50	=	2.25	nM	ALA3767923	8.65	nM	Homo sapiens
9.	ALA3764990	(8R,9S)-36	IC50	=	136	nM	ALA3767923	6.87	nM	Homo sapiens
10.	MK-4827 (Niraparib)	56, MK-4827	IC50	=	8.05	nM	ALA3767923	8.09	nM	Homo sapiens
11.	Olaparib (AZD2281, Ku-0059436)	47, KU0059436, AZD-2281	IC50	=	1.94	nM	ALA3767923	8.71	nM	Homo sapiens
12.	Rucaparib	63, AG-014699	IC50	=	1.98	nM	ALA3767923	8.70	nM	Homo sapiens
13.	Veliparib	3a, ABT-888	IC50	=	4.73	nM	ALA3767923	8.32	nM	Homo sapiens
14.	talazoparib	TALAZOPARIB	Ki	=	1.2	nM	ALA3767923	8.92	nM	Homo sapiens
15.	talazoparib	TALAZOPARIB	IC50	=	0.57	nM	ALA3767923	9.24	nM	Homo sapiens
16.	ALA3765472	64	IC50	=	3.9	nM	ALA3767923	8.41	nM	Homo sapiens
17.	ALA3763705	63	IC50	=	2.88	nM	ALA3767923	8.54	nM	Homo sapiens
18.	ALA3765661	62	IC50	=	7.62	nM	ALA3767923	8.12	nM	Homo sapiens
19.	ALA3764951	61	IC50	=	2.08	nM	ALA3767923	8.68	nM	Homo sapiens
20.	BMN 673	47	IC50	=	2.14	nM	ALA3767923	8.67	nM	Homo sapiens