# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3780847 | Abiraterone | INH | 0 | ALA3784056 | Active | % | Macaca fascicularis | ||||
2. | ALA2147041 | 9 | INH | = | 80 | % | ALA3784047 | % | Macaca fascicularis | |||
3. | ALA2147041 | 9 | INH | > | 90 | % | ALA3784045 | % | Macaca fascicularis | |||
4. | ALA3780847 | Abiraterone | Selectivity ratio | = | 2 | ALA3784031 | Macaca fascicularis | |||||
5. | ALA2147041 | 9 | Selectivity ratio | = | 11 | ALA3784031 | Macaca fascicularis | |||||
6. | ALA3780847 | Abiraterone | IC50 | = | 2 | nM | ALA3784030 | 8.70 | nM | Macaca fascicularis | ||
7. | ALA2147041 | 9 | IC50 | = | 4 | nM | ALA3784030 | 8.40 | nM | Macaca fascicularis | ||
8. | ALA3780847 | Abiraterone | IC50 | = | 3 | nM | ALA3784029 | 8.52 | nM | Macaca fascicularis | ||
9. | ALA2147041 | 9 | IC50 | = | 2 | nM | ALA3784029 | 8.70 | nM | Macaca fascicularis | ||
10. | ALA5290029 | 33 | INH | 0 | ALA5224676 | Not Active | % | Macaca fascicularis | ||||
11. | ALA5290029 | 33 | Activity | = | 7.7 | ng/dl | ALA5224675 | ng/dl | Macaca fascicularis | |||
12. | ALA5290029 | 33 | Activity | = | 27 | ng/dl | ALA5224674 | ng/dl | Macaca fascicularis | |||
13. | ALA5290029 | 33 | FC | = | 14 | ALA5224673 | Macaca fascicularis | |||||
14. | ALA5290029 | 33 | FC | = | 14 | ALA5224672 | Macaca fascicularis | |||||
15. | ALA5290029 | 33 | Activity | = | 43 | ng/dl | ALA5224671 | ng/dl | Macaca fascicularis | |||
16. | ALA5290029 | 33 | Activity | = | 83 | % | ALA5224670 | % | Macaca fascicularis | |||
17. | ALA5290029 | 33 | Ratio IC50 | = | 5 | ALA5224669 | Macaca fascicularis | |||||
18. | ALA5290029 | 33 | IC50 | = | 2 | nM | ALA5224638 | 8.70 | nM | Macaca fascicularis | ||
19. | ALA5290029 | 33 | IC50 | = | 30 | nM | ALA5224636 | 7.52 | nM | Macaca fascicularis | ||
20. | ALA5290029 | 33 | IC50 | = | 6 | nM | ALA5224635 | 8.22 | nM | Macaca fascicularis |