# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | GSK481 | 14; GSK'481 | IC50 | = | 110 | nM | ALA3789358 | 6.96 | nM | Mus musculus | ||
2. | GSK481 | 14; GSK'481 | IC50 | > | 10 | uM | ALA3789355 | nM | Mus musculus | |||
3. | RIPK1-IN-4 | 8 | IC50 | = | 0.4 | uM | ALA3789353 | 6.40 | nM | Mus musculus | ||
4. | ALA3786078 | 31 | IC50 | = | 3.2 | uM | ALA3789353 | 5.50 | nM | Mus musculus | ||
5. | GSK481 | 14; GSK'481 | IC50 | = | 3.2 | uM | ALA3789353 | 5.50 | nM | Mus musculus | ||
6. | RIPK1-IN-4 | 8 | IC50 | = | 0.05 | uM | ALA3789118 | 7.30 | nM | Mus musculus | ||
7. | ALA3786078 | 31 | IC50 | = | 1 | uM | ALA3789118 | 6.00 | nM | Mus musculus | ||
8. | GSK481 | 14; GSK'481 | IC50 | = | 3.2 | uM | ALA3789118 | 5.50 | nM | Mus musculus | ||
9. | ALA4445751 | 47 | IC50 | = | 110 | nM | ALA5152944 | 6.96 | nM | Mus musculus | ||
10. | Tozasertib | VX-680 | INH | 0 | ALA4048554 | Dose-dependent effect | % | Mus musculus | ||||
11. | ALA4076117 | 118 | INH | < | 50 | % | ALA4048560 | % | Mus musculus | |||
12. | ALA4092326 | 117 | INH | < | 50 | % | ALA4048560 | % | Mus musculus | |||
13. | ALA4064992 | 116 | INH | < | 50 | % | ALA4048560 | % | Mus musculus | |||
14. | ALA4062506 | 115 | INH | < | 50 | % | ALA4048560 | % | Mus musculus | |||
15. | ALA4102896 | 114 | INH | < | 50 | % | ALA4048560 | % | Mus musculus | |||
16. | ALA4059775 | 113 | INH | < | 50 | % | ALA4048560 | % | Mus musculus | |||
17. | ALA4095144 | 112 | INH | < | 50 | % | ALA4048560 | % | Mus musculus | |||
18. | ALA4074679 | 111 | INH | < | 50 | % | ALA4048560 | % | Mus musculus | |||
19. | ALA4077374 | 110 | INH | < | 50 | % | ALA4048560 | % | Mus musculus | |||
20. | ALA4076918 | 109 | INH | < | 50 | % | ALA4048560 | % | Mus musculus |