| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3798534 | Page no 520, R1C2 | Kd | = | 54 | uM | ALA3803058 | 4.27 | nM | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | ||
| 2. |  ALA469449 | L-fucose | IC50 | = | 2.3 | mM | ALA3803059 | nM | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | |||
| 3. |  ALA469448 | D-mannose | IC50 | = | 10.8 | uM | ALA3802801 | 4.97 | nM | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | ||
| 4. | ALA469449 | L-fucose | IC50 | = | 498 | uM | ALA3802801 | nM | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | |||
| 5. |  ALA3800313 | 10 | IC50 | = | 13 | uM | ALA3802801 | 4.89 | nM | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | ||
| 6. |  1,5-Anhydro-D-mannitol | 11 | IC50 | = | 2.9 | uM | ALA3802801 | 5.54 | nM | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | ||
| 7. |  Methyl α-D-mannopyranoside | methyl-alpha-D-mannopyranoside | IC50 | = | 7 | uM | ALA3802801 | 5.16 | nM | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | ||
| 8. |  Allyl α-D-mannopyranoside | 13 | IC50 | = | 13.6 | uM | ALA3802801 | 4.87 | nM | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | ||
| 9. |  4-Methylumbelliferylα-D-Mannopyranoside | 6 | IC50 | = | 14.5 | uM | ALA3802801 | 4.84 | nM | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | ||
| 10. |  4-Methylumbelliferyl β-D-mannopyranoside | 15 | IC50 | = | 7.4 | uM | ALA3802801 | 5.13 | nM | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | ||
| 11. |  ALA3797336 | 20 | IC50 | = | 116 | uM | ALA3802801 | nM | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | |||
| 12. |  ALA3798825 | 21 | IC50 | = | 104 | uM | ALA3802801 | nM | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | |||
| 13. |  ALA3797996 | 22 | IC50 | = | 64 | uM | ALA3802801 | 4.19 | nM | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | ||
| 14. |  ALA3800386 | 25 | IC50 | = | 19.1 | uM | ALA3802801 | 4.72 | nM | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | ||
| 15. |  ALA3797852 | 26 | IC50 | = | 13.8 | uM | ALA3802801 | 4.86 | nM | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | ||
| 16. |  ALA3800479 | 36 | INH | = | 56 | % | ALA3802803 | % | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | |||
| 17. |  2-Deoxy-2-fluoro-D-mannose | 35 | INH | 0 | ALA3802803 | Not Active | % | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | ||||
| 18. |  ALA3800459 | 34 | INH | 0 | ALA3802803 | Not Active | % | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | ||||
| 19. |  ALA3800577 | 30 | INH | 0 | ALA3802803 | Not Active | % | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) | ||||
| 20. |  ALA3797424 | 24 | INH | 0 | ALA3802803 | Not Active | % | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) |
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