| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5276374 | (S)-20a; BGB-8035 | IC50 | = | 169 | nM | ALA5251915 | 6.77 | nM | Homo sapiens | ||
| 2. |  ALA5284848 | 14d | Activity | 0 | ALA5250207 | Active | Homo sapiens | |||||
| 3. |  mobocertinib | MOBOCERTINIB | INH | > | 81 | % | ALA5238872 | % | Homo sapiens | |||
| 4. |  ALA5278295 | 63 | Emax | = | 75 | % | ALA5224322 | % | Homo sapiens | |||
| 5. | ALA5278295 | 63 | DC50 | = | 220 | nM | ALA5224321 | nM | Homo sapiens | |||
| 6. |  LDC1267 | 7; LDC1267 | % of control | < | 10 | % | ALA5212933 | % | Homo sapiens | |||
| 7. |  BMS-777607 | 10, BMS-777607 | % of control | = | 0.35 | % | ALA5212879 | % | Homo sapiens | |||
| 8. |  Afatinib dimaleate | AFATINIB DIMALEATE | Kd | = | 220 | nM | ALA5214836 | 6.66 | nM | Homo sapiens | ||
| 9. |  PQCA | 4i | % of control | = | 49 | % | ALA5214249 | % | Homo sapiens | |||
| 10. |  FM-381 | FM-381 | % of inhibition | = | 43 | % | ALA5213576 | % | Homo sapiens | |||
| 11. |  Acalabrutinib (ACP-196) | ACALABRUTINIB | IC50 | > | 10 | uM | ALA5213044 | nM | Homo sapiens | |||
| 12. |  Zanubrutinib (BGB-3111) | BDBM250082 | IC50 | = | 1.13 | nM | ALA5210353 | 8.95 | nM | Homo sapiens | ||
| 13. | Zanubrutinib (BGB-3111) | BDBM250082 | IC50 | = | 360 | nM | ALA5209938 | 6.44 | nM | Homo sapiens | ||
| 14. |  ALA5204121 | 20 | INH | 0 | ALA5156316 | NA | % | Homo sapiens | ||||
| 15. |  ALA5169523 | 25 | INH | = | 101 | % | ALA5156281 | % | Homo sapiens | |||
| 16. | ALA5169523 | 25 | INH | 0 | ALA5156280 | Active | % | Homo sapiens | ||||
| 17. | ALA5169523 | 25 | IC50 | = | 12 | nM | ALA5156276 | 7.92 | nM | Homo sapiens | ||
| 18. |  ALA5202420 | 23 | IC50 | = | 5.5 | nM | ALA5156276 | 8.26 | nM | Homo sapiens | ||
| 19. |  ALA5184304 | 21 | IC50 | = | 63 | nM | ALA5156276 | 7.20 | nM | Homo sapiens | ||
| 20. |  2-methyl-N-(2-{[3-(prop-2-enamido)phenyl]amino}pyrimidin-5-yl)-5-[3-(trifluoromethyl)benzamido]benzamide | 31 | IC50 | = | 15 | nM | ALA5156276 | 7.82 | nM | Homo sapiens |
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