# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2171701 | 1c, MmPPOX | XI50 | = | 1.48 | molar excess | ALA2174471 | molar excess | Homo sapiens | |||
2. | ALA2171700 | 2c, MpPPOX | XI50 | = | 0.93 | molar excess | ALA2174471 | molar excess | Homo sapiens | |||
3. | ALA2171699 | 3c, MPOX | XI50 | = | 0.77 | molar excess | ALA2174471 | molar excess | Homo sapiens | |||
4. | Orlistat | 1 (orlistat) | XI50 | = | 0.78 | molar excess | ALA2174471 | molar excess | Homo sapiens | |||
5. | ALA2171701 | 1c, MmPPOX | t1/2 | = | 0.9 | min | ALA2174462 | hr | Homo sapiens | |||
6. | ALA2171700 | 2c, MpPPOX | t1/2 | = | 1.43 | min | ALA2174462 | hr | Homo sapiens | |||
7. | ALA2171699 | 3c, MPOX | t1/2 | = | 1 | min | ALA2174462 | hr | Homo sapiens | |||
8. | Orlistat | 1 (orlistat) | t1/2 | = | 0.52 | min | ALA2174462 | hr | Homo sapiens | |||
9. | ALA2171701 | 1c, MmPPOX | INH | = | 54.5 | % | ALA2174365 | % | Homo sapiens | |||
10. | ALA2171701 | 1c, MmPPOX | INH | = | 84.7 | % | ALA2174364 | % | Homo sapiens | |||
11. | ALA2171700 | 2c, MpPPOX | INH | = | 77.1 | % | ALA2174365 | % | Homo sapiens | |||
12. | ALA2171700 | 2c, MpPPOX | INH | = | 78.6 | % | ALA2174364 | % | Homo sapiens | |||
13. | ALA2171699 | 3c, MPOX | INH | = | 71.6 | % | ALA2174365 | % | Homo sapiens | |||
14. | ALA2171699 | 3c, MPOX | INH | = | 81.3 | % | ALA2174364 | % | Homo sapiens | |||
15. | Orlistat | 1 (orlistat) | INH | = | 80.1 | % | ALA2174365 | % | Homo sapiens | |||
16. | Orlistat | 1 (orlistat) | INH | = | 83.6 | % | ALA2174364 | % | Homo sapiens | |||
17. | ALA2171701 | 1c, MmPPOX | INH | 0 | ALA2174359 | Active | % | Homo sapiens | ||||
18. | ALA459683 | 19 | IC50 | > | 100 | uM | ALA969705 | nM | Homo sapiens | |||
19. | ALA459684 | 20 | IC50 | > | 100 | uM | ALA969705 | nM | Homo sapiens | |||
20. | ALA461945 | 21 | IC50 | > | 100 | uM | ALA969705 | nM | Homo sapiens |