# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2012574 | 42, LDN-211898 | INH | = | 12 | % | ALA2014139 | % | Homo sapiens | |||
2. | Repotrectinib (TPX-0005) | REPOTRECTINIB | IC50 | = | 63.6 | nM | ALA4668366 | 7.20 | nM | Homo sapiens | ||
3. | Brigatinib | BRIGATINIB | IC50 | = | 184 | nM | ALA4668356 | 6.74 | nM | Homo sapiens | ||
4. | Brigatinib | BRIGATINIB | IC50 | = | 41 | nM | ALA4668355 | 7.39 | nM | Homo sapiens | ||
5. | ALA3651854 | BDBM107057 | IC50 | = | 0.01 | uM | ALA4716829 | 8.00 | nM | Homo sapiens | ||
6. | ALA4760809 | 18; SIAI5117 | IC50 | = | 146.4 | nM | ALA4686178 | 6.83 | nM | Homo sapiens | ||
7. | ALA4585232 | Y | IC50 | > | 1000 | nM | ALA4418508 | nM | Homo sapiens | |||
8. | ALA4456322 | X | IC50 | = | 821 | nM | ALA4418508 | 6.09 | nM | Homo sapiens | ||
9. | ALA3687225 | BDBM144320 | IC50 | = | 16 | nM | ALA4418508 | 7.80 | nM | Homo sapiens | ||
10. | ALA3687224 | BDBM144319 | IC50 | = | 14 | nM | ALA4418508 | 7.85 | nM | Homo sapiens | ||
11. | ALA3687223 | BDBM144318 | IC50 | = | 4.7 | nM | ALA4418508 | 8.33 | nM | Homo sapiens | ||
12. | ALA3687222 | BDBM144317 | IC50 | = | 39 | nM | ALA4418508 | 7.41 | nM | Homo sapiens | ||
13. | ALA3687221 | BDBM144316 | IC50 | = | 14 | nM | ALA4418508 | 7.85 | nM | Homo sapiens | ||
14. | Gilteritinib | GILTERITINIB | IC50 | = | 5.7 | nM | ALA4418508 | 8.24 | nM | Homo sapiens | ||
15. | ALA3687220 | BDBM144314 | IC50 | = | 23 | nM | ALA4418508 | 7.64 | nM | Homo sapiens | ||
16. | ALA3687219 | BDBM144313 | IC50 | = | 25 | nM | ALA4418508 | 7.60 | nM | Homo sapiens | ||
17. | ALA3687218 | BDBM144312 | IC50 | = | 27 | nM | ALA4418508 | 7.57 | nM | Homo sapiens | ||
18. | ALA3687217 | BDBM144311 | IC50 | = | 7.7 | nM | ALA4418508 | 8.11 | nM | Homo sapiens | ||
19. | ALA3687216 | BDBM144310 | IC50 | = | 24 | nM | ALA4418508 | 7.62 | nM | Homo sapiens | ||
20. | ALA3687215 | BDBM144309 | IC50 | = | 19 | nM | ALA4418508 | 7.72 | nM | Homo sapiens |