# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Nicotine | 2 | Ki | = | 167 | nM | ALA2187482 | 6.78 | nM | Mus musculus | ||
2. | ALA1783888 | 23b | EC50 | = | 41 | uM | ALA1785124 | 4.39 | nM | Mus musculus | ||
3. | ALA3215819 | 23a | EC50 | = | 21 | uM | ALA1785124 | 4.68 | nM | Mus musculus | ||
4. | ALA1783886 | 20b | EC50 | = | 2.4 | uM | ALA1785124 | 5.62 | nM | Mus musculus | ||
5. | RJR 2429 dihydrochloride | 20a | EC50 | = | 0.4 | uM | ALA1785124 | 6.40 | nM | Mus musculus | ||
6. | ALA1783884 | 15b | EC50 | = | 161 | uM | ALA1785124 | nM | Mus musculus | |||
7. | ALA1783883 | 15a | EC50 | = | 16 | uM | ALA1785124 | 4.80 | nM | Mus musculus | ||
8. | ALA1783882 | 11b | EC50 | = | 28 | uM | ALA1785124 | 4.55 | nM | Mus musculus | ||
9. | ALA1783881 | 11a | EC50 | = | 3.3 | uM | ALA1785124 | 5.48 | nM | Mus musculus | ||
10. | ALA1783880 | 8b | EC50 | = | 9.5 | uM | ALA1785124 | 5.02 | nM | Mus musculus | ||
11. | ALA1783879 | 8a | EC50 | = | 218 | uM | ALA1785124 | nM | Mus musculus | |||
12. | ALA1783878 | 5b | EC50 | = | 34 | uM | ALA1785124 | 4.47 | nM | Mus musculus | ||
13. | ALA1782074 | 5a | EC50 | = | 5.6 | uM | ALA1785124 | 5.25 | nM | Mus musculus | ||
14. | ALA1783888 | 23b | Emax | = | 35 | % | ALA1785683 | % | Mus musculus | |||
15. | ALA3215819 | 23a | Emax | = | 71 | % | ALA1785683 | % | Mus musculus | |||
16. | ALA1783886 | 20b | Emax | = | 95 | % | ALA1785683 | % | Mus musculus | |||
17. | RJR 2429 dihydrochloride | 20a | Emax | = | 106 | % | ALA1785683 | % | Mus musculus | |||
18. | ALA1783884 | 15b | Emax | = | 97 | % | ALA1785683 | % | Mus musculus | |||
19. | ALA1783883 | 15a | Emax | = | 58 | % | ALA1785683 | % | Mus musculus | |||
20. | ALA1783882 | 11b | Emax | = | 106 | % | ALA1785683 | % | Mus musculus |