Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	PF‐06928215	PF-06928215	Kd	=	0.2	uM	ALA4433342	6.70		nM	Homo sapiens
2.	ALA4065757	15	Kd	=	170	uM	ALA4433342	3.77		nM	Homo sapiens
3.	ALA4062994	18	IC50	=	21	uM	ALA4031180	4.68		nM	Homo sapiens
4.	ALA4084664	19	IC50	=	8.1	uM	ALA4031180	5.09		nM	Homo sapiens
5.	PF‐06928215	PF-06928215	IC50	=	2	uM	ALA4031180	5.70		nM	Homo sapiens
6.	ALA4065757	15	IC50	=	78	uM	ALA4031181	4.11		nM	Homo sapiens
7.	ALA4085628	16	IC50	=	125	uM	ALA4031181			nM	Homo sapiens
8.	ALA4103560	17	IC50	=	15.1	uM	ALA4031181	4.82		nM	Homo sapiens
9.	ALA4062994	18	IC50	=	10.6	uM	ALA4031181	4.97		nM	Homo sapiens
10.	ALA4084664	19	IC50	=	17.5	uM	ALA4031181	4.76		nM	Homo sapiens
11.	PF‐06928215	PF-06928215	IC50	=	4.9	uM	ALA4031181	5.31		nM	Homo sapiens
12.	ALA4103560	17	INH		0		ALA4031182		Not Active	%	Homo sapiens
13.	ALA4062994	18	INH		0		ALA4031182		Not Active	%	Homo sapiens
14.	ALA4084664	19	INH		0		ALA4031182		Not Active	%	Homo sapiens
15.	PF‐06928215	PF-06928215	INH		0		ALA4031182		Not Active	%	Homo sapiens
16.	BX-795	BX-795	IC50	=	60	nM	ALA4031182	7.22		nM	Homo sapiens
17.	ALA4065757	15	Kd	=	171	uM	ALA4031179			nM	Homo sapiens
18.	ALA4085628	16	Kd	=	78	uM	ALA4031179	4.11		nM	Homo sapiens
19.	ALA4103560	17	Kd	=	12.5	uM	ALA4031179	4.90		nM	Homo sapiens
20.	ALA4062994	18	Kd	=	6.7	uM	ALA4031179	5.17		nM	Homo sapiens