Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	Cobimetinib	1, XL518, GDC-0973	IC50	=	53	nM	ALA5213150	7.28		nM	Homo sapiens
2.	Abemaciclib	ABEMACICLIB	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
3.	Vemurafenib (PLX4032, RG7204)	VEMURAFENIB	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
4.	ALA4084193	RDEA-436	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
5.	CH5183284 (Debio-1347)	8; CH5183284; Debio 1347	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
6.	Telatinib	BAY-579352	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
7.	TG 100801	12, TG100801	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
8.	BYL719	8, NVP-BYL719	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
9.	Y-33075	23, Y-39983	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
10.	SNS-032 (BMS-387032)	21	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
11.	Tideglusib	TIDEGLUSIB	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
12.	MK-8776 (SCH 900776)	29	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
13.	Imatinib (STI571)	1	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
14.	CEP-32496	40, CEP-32496	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
15.	Palbociclib	43(table 3)	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
16.	Sunitinib	12b	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
17.	AZD8931 (Sapitinib)	2, AZD8931	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
18.	K-252a	2 (K-252a)	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
19.	Entrectinib	SID103905026	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens
20.	GSK1070916	GSK-1070916	Kd apparent	>	30000	nM	ALA3991612		Inactive	nM	Homo sapiens