# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5199854 | 10 | IC50 | < | 500 | nM | ALA5127721 | nM | Homo sapiens | |||
2. | ALA5191365 | 9 | IC50 | < | 500 | nM | ALA5127721 | nM | Homo sapiens | |||
3. | ALA5192230 | 8 | IC50 | = | 62.07 | nM | ALA5127720 | 7.21 | nM | Homo sapiens | ||
4. | ALA5178041 | 7 | IC50 | = | 103.9 | nM | ALA5127720 | 6.98 | nM | Homo sapiens | ||
5. | ALA5183050 | 6 | IC50 | = | 10 | nM | ALA5127718 | 8.00 | nM | Homo sapiens | ||
6. | ALA5171719 | 5 | IC50 | = | 4 | nM | ALA5127718 | 8.40 | nM | Homo sapiens | ||
7. | ALA5193835 | 4 | IC50 | = | 3 | nM | ALA5127718 | 8.52 | nM | Homo sapiens | ||
8. | ALA5173530 | 3 | IC50 | = | 15 | nM | ALA5127718 | 7.82 | nM | Homo sapiens | ||
9. | ALA5182811 | 2 | IC50 | = | 379 | nM | ALA5127715 | 6.42 | nM | Homo sapiens | ||
10. | ALA5178144 | 1 | IC50 | = | 938 | nM | ALA5127715 | 6.03 | nM | Homo sapiens | ||
11. | ALA5181958 | 29 | Activity | = | 59 | % | ALA5117585 | % | Homo sapiens | |||
12. | ALA5182800 | 22 | Activity | = | 91 | % | ALA5117585 | % | Homo sapiens | |||
13. | ALA5188172 | 3 | Activity | = | 96 | % | ALA5117585 | % | Homo sapiens | |||
14. | Elimusertib (BAY-1895344) | BAY-1895344 | IC50 | = | 7 | nM | ALA4775106 | 8.15 | nM | Homo sapiens | ||
15. | ALA4793380 | 17d | Activity | = | 92 | % | ALA4766982 | % | Homo sapiens | |||
16. | ALA4293269 | A90 | IC50 | = | 1 | nM | ALA4256221 | 9.00 | nM | Homo sapiens | ||
17. | ALA4282665 | A74 | IC50 | = | 10 | nM | ALA4256221 | 8.00 | nM | Homo sapiens | ||
18. | ALA4280068 | A15 | IC50 | < | 1 | nM | ALA4256221 | nM | Homo sapiens | |||
19. | ALA4287971 | A10 | IC50 | = | 10 | nM | ALA4256221 | 8.00 | nM | Homo sapiens | ||
20. | ALA4295245 | A6 | IC50 | < | 1 | nM | ALA4256221 | nM | Homo sapiens |