# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2431004 | (R)-(-)5a | INH | 0 | ALA4407825 | Active | % | Plasmodium falciparum (isolate 3D7) | ||||
2. | ALA2431004 | (R)-(-)5a | INH | 0 | ALA4407824 | Active | % | Plasmodium falciparum (isolate 3D7) | ||||
3. | ALA2431003 | S-(+)5a | INH | 0 | ALA4407824 | Active | % | Plasmodium falciparum (isolate 3D7) | ||||
4. | ALA2431003 | S-(+)5a | INH | 0 | ALA4407825 | Active | % | Plasmodium falciparum (isolate 3D7) | ||||
5. | ALA4437978 | 7h | IC50 | = | 0.22 | uM | ALA4407816 | 6.66 | nM | Plasmodium falciparum (isolate 3D7) | ||
6. | ALA4578312 | 7g | IC50 | = | 65 | uM | ALA4407816 | 4.19 | nM | Plasmodium falciparum (isolate 3D7) | ||
7. | ALA4458458 | 7f | IC50 | = | 3.7 | uM | ALA4407816 | 5.43 | nM | Plasmodium falciparum (isolate 3D7) | ||
8. | ALA4462089 | 7e | IC50 | = | 5.5 | uM | ALA4407816 | 5.26 | nM | Plasmodium falciparum (isolate 3D7) | ||
9. | ALA4564404 | 7d | IC50 | = | 1 | uM | ALA4407816 | 6.00 | nM | Plasmodium falciparum (isolate 3D7) | ||
10. | ALA4572338 | 7c | IC50 | = | 823 | uM | ALA4407816 | nM | Plasmodium falciparum (isolate 3D7) | |||
11. | ALA4545211 | 7b | IC50 | = | 8.5 | uM | ALA4407816 | 5.07 | nM | Plasmodium falciparum (isolate 3D7) | ||
12. | ALA4452553 | 7a | IC50 | = | 7.6 | uM | ALA4407816 | 5.12 | nM | Plasmodium falciparum (isolate 3D7) | ||
13. | Fosmidomycin sodium salt | 1 | IC50 | = | 0.16 | uM | ALA4407816 | 6.80 | nM | Plasmodium falciparum (isolate 3D7) | ||
14. | ALA4474216 | rac-5j | IC50 | = | 0.029 | uM | ALA4407816 | 7.54 | nM | Plasmodium falciparum (isolate 3D7) | ||
15. | ALA4567904 | rac-5i | IC50 | = | 0.011 | uM | ALA4407816 | 7.96 | nM | Plasmodium falciparum (isolate 3D7) | ||
16. | ALA4544750 | rac-5h | IC50 | = | 0.024 | uM | ALA4407816 | 7.62 | nM | Plasmodium falciparum (isolate 3D7) | ||
17. | ALA4447571 | rac-5g | IC50 | = | 0.032 | uM | ALA4407816 | 7.50 | nM | Plasmodium falciparum (isolate 3D7) | ||
18. | ALA4592986 | rac-5f | IC50 | = | 0.02 | uM | ALA4407816 | 7.70 | nM | Plasmodium falciparum (isolate 3D7) | ||
19. | ALA4590343 | rac-5e | IC50 | = | 0.013 | uM | ALA4407816 | 7.89 | nM | Plasmodium falciparum (isolate 3D7) | ||
20. | ALA4206225 | 18a | INH | 0 | ALA4201420 | Active | % | Plasmodium falciparum (isolate 3D7) |