# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | GZD824 | 10a, GZD824 | INH | 0 | ALA2318542 | Dose-dependent effect | % | Mus musculus | ||||
2. | Imatinib (STI571) | 1 | INH | 0 | ALA2318542 | Not Active | % | Mus musculus | ||||
3. | Nilotinib (AMN-107) | 38 | INH | 0 | ALA2318542 | Not Active | % | Mus musculus | ||||
4. | Dasatinib | 2, BMS-354825 | INH | 0 | ALA2318542 | Not Active | % | Mus musculus | ||||
5. | GZD824 | 10a, GZD824 | INH | 0 | ALA2318541 | Dose-dependent effect | % | Mus musculus | ||||
6. | Imatinib (STI571) | 1 | INH | 0 | ALA2318541 | Not Active | % | Mus musculus | ||||
7. | Nilotinib (AMN-107) | 38 | INH | 0 | ALA2318541 | Not Active | % | Mus musculus | ||||
8. | Dasatinib | 2, BMS-354825 | INH | 0 | ALA2318541 | Not Active | % | Mus musculus | ||||
9. | GZD824 | 10a, GZD824 | INH | 0 | ALA2318540 | Dose-dependent effect | % | Mus musculus | ||||
10. | Imatinib (STI571) | 1 | INH | 0 | ALA2318540 | Not Active | % | Mus musculus | ||||
11. | Nilotinib (AMN-107) | 38 | INH | 0 | ALA2318540 | Not Active | % | Mus musculus | ||||
12. | Dasatinib | 2, BMS-354825 | INH | 0 | ALA2318540 | Not Active | % | Mus musculus | ||||
13. | TC-S 7001 | SID103905649 | % inhibition | 33 | % | ALA4881484 | Not Active | % | Mus musculus | |||
14. | Regorafenib (BAY 73-4506) | 2, BAY-734506 | Activity | = | 22 | % | ALA4725567 | % | Mus musculus | |||
15. | Regorafenib (BAY 73-4506) | 2, BAY-734506 | Activity | = | -7 | % | ALA4725541 | % | Mus musculus | |||
16. | Regorafenib (BAY 73-4506) | 2, BAY-734506 | Activity | = | -1 | % | ALA4725507 | % | Mus musculus | |||
17. | ALA3735648 | 15b | IC50 | > | 1000 | nM | ALA3830424 | nM | Mus musculus | |||
18. | LY2157299 | GALUNISERTIB | IC50 | 0 | ALA4270676 | Not Determined | Mus musculus | |||||
19. | RepSox | 19 | IC50 | = | 21 | uM | ALA4270676 | 4.68 | nM | Mus musculus | ||
20. | ALA4291439 | 8m | IC50 | = | 20 | uM | ALA4270676 | 4.70 | nM | Mus musculus |