# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4642168 | DAS-6-2-2-6-CRBN; DA-6-2-2-6-CRBN | EC50 | = | 4.4 | nM | ALA4672970 | 8.36 | nM | Homo sapiens | ||
2. | ALA4742867 | BOS-6-(2-)5-2-CRBN | Activity | > | 60 | % | ALA4672968 | % | Homo sapiens | |||
3. | ALA4748640 | BOS-6-2-2-CRBN | Activity | > | 60 | % | ALA4672968 | % | Homo sapiens | |||
4. | ALA4742759 | BOS-6-2-2-6-CRBN | Activity | > | 60 | % | ALA4672968 | % | Homo sapiens | |||
5. | ALA4747034 | DAS-6-(2-)5-2-CRBN | Activity | > | 60 | % | ALA4672968 | % | Homo sapiens | |||
6. | ALA4642168 | DAS-6-2-2-6-CRBN; DA-6-2-2-6-CRBN | Activity | > | 60 | % | ALA4672968 | % | Homo sapiens | |||
7. | ALA4742867 | BOS-6-(2-)5-2-CRBN | Activity | > | 80 | % | ALA4672967 | % | Homo sapiens | |||
8. | ALA4748640 | BOS-6-2-2-CRBN | Activity | > | 80 | % | ALA4672967 | % | Homo sapiens | |||
9. | ALA4742759 | BOS-6-2-2-6-CRBN | Activity | > | 80 | % | ALA4672967 | % | Homo sapiens | |||
10. | ALA4747034 | DAS-6-(2-)5-2-CRBN | Activity | > | 80 | % | ALA4672967 | % | Homo sapiens | |||
11. | ALA4642168 | DAS-6-2-2-6-CRBN; DA-6-2-2-6-CRBN | Activity | > | 80 | % | ALA4672967 | % | Homo sapiens | |||
12. | ALA4742867 | BOS-6-(2-)5-2-CRBN | Kd | = | 0.38 | nM | ALA4672966 | 9.42 | nM | Homo sapiens | ||
13. | ALA4748640 | BOS-6-2-2-CRBN | Kd | = | 0.28 | nM | ALA4672966 | 9.55 | nM | Homo sapiens | ||
14. | ALA4742759 | BOS-6-2-2-6-CRBN | Kd | = | 0.91 | nM | ALA4672966 | 9.04 | nM | Homo sapiens | ||
15. | ALA4747034 | DAS-6-(2-)5-2-CRBN | Kd | = | 0.26 | nM | ALA4672966 | 9.59 | nM | Homo sapiens | ||
16. | ALA4642168 | DAS-6-2-2-6-CRBN; DA-6-2-2-6-CRBN | Kd | = | 0.6 | nM | ALA4672966 | 9.22 | nM | Homo sapiens | ||
17. | ALA4742867 | BOS-6-(2-)5-2-CRBN | Kd | = | 0.13 | nM | ALA4672965 | 9.89 | nM | Homo sapiens | ||
18. | ALA4748640 | BOS-6-2-2-CRBN | Kd | = | 0.11 | nM | ALA4672965 | 9.96 | nM | Homo sapiens | ||
19. | ALA4742759 | BOS-6-2-2-6-CRBN | Kd | = | 0.55 | nM | ALA4672965 | 9.26 | nM | Homo sapiens | ||
20. | ALA4747034 | DAS-6-(2-)5-2-CRBN | Kd | = | 0.23 | nM | ALA4672965 | 9.64 | nM | Homo sapiens |