| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  SIAIS178 | 19; SIAIS178 | Activity | 0 | ALA4415998 | Dose-dependent effect | Homo sapiens | |||||
| 2. |  PROTAC RIPK degrader-2 | 3 | Emax | > | 95 | % | ALA4388599 | % | Homo sapiens | |||
| 3. | PROTAC RIPK degrader-2 | 3 | DC50 | = | 1.4 | nM | ALA4388598 | nM | Homo sapiens | |||
| 4. | PROTAC RIPK degrader-2 | 3 | Emax | > | 95 | % | ALA4349406 | % | Homo sapiens | |||
| 5. | PROTAC RIPK degrader-2 | 3 | DC50 | = | 1.4 | nM | ALA4349407 | nM | Homo sapiens | |||
| 6. |  ALA4205154 | 2 | IC50 | = | 1.4 | nM | ALA4190484 | 8.85 | nM | Homo sapiens | ||
| 7. | ALA4205154 | 2 | Imax | > | 95 | % | ALA4190485 | % | Homo sapiens | |||
| 8. | PROTAC RIPK degrader-2 | 3 | pIC50 | = | 7 | ALA4832927 | 7.00 | nM | Homo sapiens | |||
| 9. | PROTAC RIPK degrader-2 | 3 | DC50 | = | 1.5 | nM | ALA4832924 | nM | Homo sapiens | |||
| 10. | PROTAC RIPK degrader-2 | 3 | DC50 | = | 1 | nM | ALA4026936 | nM | Homo sapiens |
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