# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ARV-771 | 5 | DC50 | < | 5 | nM | ALA4388593 | nM | Homo sapiens | |||
2. | ALA4443814 | 48 | DC50 | = | 10 | nM | ALA4349415 | nM | Homo sapiens | |||
3. | ARV-771 | 5 | DC50 | < | 5 | nM | ALA4349409 | nM | Homo sapiens | |||
4. | ARV-771 | 5 | IC50 | < | 5 | nM | ALA4190491 | nM | Homo sapiens | |||
5. | ALA5071597 | 25; ET-OARV-771, Diastereomeric mixture | Emax | = | 85 | % | ALA5054796 | % | Homo sapiens | |||
6. | ALA5093148 | 24; ME-OARV-771, Diastereomeric mixture | Emax | = | 91 | % | ALA5054796 | % | Homo sapiens | |||
7. | ALA5086180 | 23; Et-OMZ1, Diastereomeric mixture | Emax | = | 96 | % | ALA5054796 | % | Homo sapiens | |||
8. | ALA5085093 | 22; ME-OMZ1, Diastereomeric mixture | Emax | = | 96 | % | ALA5054796 | % | Homo sapiens | |||
9. | ALA5087074 | 21; ET-ARV-771, Diastereomeric mixture | Emax | = | 51 | % | ALA5054796 | % | Homo sapiens | |||
10. | ALA5070120 | 20; ME-ARV-771, Diastereomeric mixture | Emax | = | 60 | % | ALA5054796 | % | Homo sapiens | |||
11. | ALA5091753 | 19; ET-MZ1, Diastereomeric mixture | Emax | = | 80 | % | ALA5054796 | % | Homo sapiens | |||
12. | ALA5090488 | 18; ME-MZ1, Diastereomeric mixture | Emax | = | 92 | % | ALA5054796 | % | Homo sapiens | |||
13. | ALA5081978 | 48; AGB3 | Emax | = | 96 | % | ALA5054796 | % | Homo sapiens | |||
14. | ALA5089280 | 47; AGB2 | Emax | = | 98 | % | ALA5054796 | % | Homo sapiens | |||
15. | ALA5089544 | 46; AGB1 | Emax | = | 97 | % | ALA5054796 | % | Homo sapiens | |||
16. | ALA5071597 | 25; ET-OARV-771, Diastereomeric mixture | pDC50 | = | 7.8 | ALA5054795 | Homo sapiens | |||||
17. | ALA5093148 | 24; ME-OARV-771, Diastereomeric mixture | pDC50 | = | 8.3 | ALA5054795 | Homo sapiens | |||||
18. | ALA5086180 | 23; Et-OMZ1, Diastereomeric mixture | pDC50 | = | 7.9 | ALA5054795 | Homo sapiens | |||||
19. | ALA5085093 | 22; ME-OMZ1, Diastereomeric mixture | pDC50 | = | 7.7 | ALA5054795 | Homo sapiens | |||||
20. | ALA5087074 | 21; ET-ARV-771, Diastereomeric mixture | pDC50 | = | 5.7 | ALA5054795 | Homo sapiens |